[Half-life calculator · Testosterone Propionate]

When does testosterone propionate peak and reach steady state?

Reviewed · Modeled estimates

Short answer: Testosterone propionate has a half-life of about 20 hours (Nieschlag E, et al. 1976) and reaches steady state after about 4.2 days of regular dosing. We could not confirm a published time to peak for testosterone propionate, so we do not state one. With the same total per week, Dose Track's model gives a peak-to-trough swing of about 2.03:1 daily and about 4.38:1 every other day.

Every other day vs daily: how do testosterone propionate levels compare?

Estimated Testosterone Propionate level: Every other day vs Daily (0.5× amount)Modeled level over 2 weeks with a half-life of 20 hours. Steady state after about 4.2 days.00.511.5day 0day 1day 2day 3day 4day 5day 6day 7day 8day 9day 10day 11day 12day 13day 14Relative level (1 = one dose)≈ steady state (5 half-lives)Every other dayDaily (0.5× amount)

Relative units: 1 on the scale is one full dose. There is no FDA label dose for this use, so the chart shows the shape of the curve, not an amount. Dashed line: 5 half-lives. Change the amount or schedule in the calculator.

When does testosterone propionate peak after a dose?

We could not confirm a published time to peak for testosterone propionate, so we do not state one. The chart follows the app: for an oil injection into muscle it counts what is still in the injection depot plus what is in blood, so the modeled total is highest right after each shot and then falls as the depot releases and the body clears it. The curve still needs a rise time, so it uses the app's modeling estimate; treat the shape of the first day or two as approximate.

How long does testosterone propionate take to reach steady state?

With regular dosing at a fixed amount and interval, levels climb toward steady state by the same fraction every half-life, whatever the dose. At a half-life of about 20 hours:

Time from the first dose to each share of steady state, testosterone propionate (half-life 20 hours).
Share of steady stateHalf-livesTime
50%120 hours
75%240 hours
90%3.32.8 days
97% (Dose Track's steady-state rule)54.2 days

How much do testosterone propionate levels swing between doses?

The longer the gap between doses compared with the half-life, the bigger the swing from peak to trough and the less the levels build up. These ratios do not depend on the amount.

Steady-state peak:trough and build-up by dosing interval, testosterone propionate, in Dose Track's model.
IntervalPeak : troughBuild-up vs one dose
Daily2.03 : 11.77×
Every other day4.38 : 11.23×
Twice weekly14.7 : 11.06×
Weekly267 : 11×
Every 2 weeksover 1,000 : 11×

Build-up is the accumulation ratio 1 / (1 − e−k·τ), with k = ln 2 / half-life and τ the interval.

How long does testosterone propionate stay in your system?

After the last dose, about half is gone every 20 hours. After 5 half-lives, about 4.2 days, roughly 97% has cleared in the model.

Where do these numbers come from?

There is no current FDA label for testosterone propionate injection. Small human studies of injection into muscle in oil point to an effective half-life of roughly 1 day: testosterone stayed above the lower limit of normal for 1 day after 25 mg and 2 days after 50 mg (Nieschlag 1976), and were back to baseline within 4 days after 100 mg (Anderson 1993). This is how long the oil depot keeps releasing, not how fast the body clears testosterone itself. No study reports a measured time to peak; testosterone was highest at the 8-hour sample in one study, and the ester stayed level from 3 to 36 hours in another (Fujioka 1986), so we do not list a single number.

The curve uses the half-life, time to peak, route and bioavailability built into the Dose Track app for testosterone propionate, and the same one-compartment model with first-order absorption. These are modeled estimates from published half-lives, drawn with the same one-compartment model as the Dose Track app. Real levels vary from person to person, and only a lab test measures them. This is not medical advice and not a dosing recommendation; dosing decisions belong with you and your prescriber.

Vial sizes and syringe math are in the Testosterone Propionate guide.

Frequently asked questions

When does testosterone propionate peak after a dose?+
We could not confirm a published time to peak for testosterone propionate, so we do not give one. Dose Track counts what is still in the oil depot as well as what is in blood, so its modeled total is highest right after each injection; blood levels rise as the depot releases. Individual timing varies with the injection site, the amount and the person.
How long does testosterone propionate take to reach steady state?+
About 4.2 days of regular dosing at the same amount and interval, which is 5 half-lives. With a half-life of about 20 hours, levels reach about 50% of steady state after 20 hours and about 90% after 2.8 days. Changing the dose or interval starts a new climb toward a new steady state.
Does splitting testosterone propionate into more frequent doses keep levels steadier?+
In the model, it narrows the swing but not the average. With the same total per week, the peak-to-trough ratio at steady state is about 2.03:1 daily, about 4.38:1 every other day. Which schedule to use is a decision for you and your prescriber.
How long does testosterone propionate stay in your system after the last dose?+
Roughly 5 half-lives, about 4.2 days, until about 97% has cleared in the model. Half is gone about 20 hours after levels start falling. Real clearance varies from person to person, and a drug can still have effects after levels are low.
Is this chart my actual testosterone propionate level?+
No. It is a modeled estimate from a published half-life, using the same one-compartment model as the Dose Track app. Real levels vary with body weight, injection site, kidney and liver function and other factors, and only a lab test measures them. It is not medical advice.