Oxandrolone Half-Life: Peak and Steady State Chart
[Half-life calculator · Oxandrolone]

When does oxandrolone peak and reach steady state?

Reviewed · Modeled estimates

Short answer: Oxandrolone has a half-life of about 10.4 hours (Oxandrin (oxandrolone tablets, USP) label) and reaches steady state after about 2.2 days of regular dosing. We could not confirm a published time to peak for oxandrolone, so we do not state one. With the same total per week, Dose Track's model gives a peak-to-trough swing of about 2.07:1 every 0.5 days and about 4.57:1 daily.

Daily vs every 0.5 days: how do oxandrolone levels compare?

Estimated Oxandrolone level: 10 mg daily vs 5 mg every 0.5 daysModeled level over 4 days with a half-life of 10 hours. Steady state after about 2.2 days.02.557.51012.5day 0day 1day 2day 3day 4Est. amount in system (mg)≈ steady state (5 half-lives)10 mg daily5 mg every 0.5 days

The former Oxandrin label gave adults 2.5 to 20 mg a day, split into 2 to 4 doses, for 2 to 4 weeks at a time. The chart compares 10 mg once daily with 5 mg twice daily. US approval has been withdrawn. Source: Oxandrin (oxandrolone tablets, USP) label. Bioavailability 97% as in the app. Dashed line: 5 half-lives. Change the amount or schedule in the calculator.

When does oxandrolone peak after a dose?

We could not confirm a published time to peak for oxandrolone, so we do not state one. The curve still needs a rise time, so it uses the app's modeling estimate; treat the shape of the first day or two as approximate.

How long does oxandrolone take to reach steady state?

With regular dosing at a fixed amount and interval, levels climb toward steady state by the same fraction every half-life, whatever the dose. At a half-life of about 10.4 hours:

Time from the first dose to each share of steady state, oxandrolone (half-life 10 hours).
Share of steady stateHalf-livesTime
50%110.4 hours
75%220.8 hours
90%3.334.5 hours
97% (Dose Track's steady-state rule)52.2 days

How much do oxandrolone levels swing between doses?

The longer the gap between doses compared with the half-life, the bigger the swing from peak to trough and the less the levels build up. These ratios do not depend on the amount.

Steady-state peak:trough and build-up by dosing interval, oxandrolone, in Dose Track's model.
IntervalPeak : troughBuild-up vs one dose
Daily4.57 : 11.25×
Every other day22.6 : 11.04×
Twice weekly249 : 11×
Weeklyover 1,000 : 11×
Every 2 weeksover 1,000 : 11×

Build-up is the accumulation ratio 1 / (1 − e−k·τ), with k = ln 2 / half-life and τ the interval.

How long does oxandrolone stay in your system?

After the last dose, about half is gone every 10 hours. After 5 half-lives, about 2.2 days, roughly 97% has cleared in the model.

Where do these numbers come from?

The former Oxandrin label reports a mean elimination half-life of 10.4 hours in younger volunteers and 13.3 hours in elderly volunteers; Dose Track uses 10.4 hours, the figure for younger adults. The label gives no time to peak, so we do not list one.

The curve uses the half-life, time to peak, route and bioavailability built into the Dose Track app for oxandrolone, and the same one-compartment model with first-order absorption. These are modeled estimates from published half-lives, drawn with the same one-compartment model as the Dose Track app. Real levels vary from person to person, and only a lab test measures them. This is not medical advice and not a dosing recommendation; dosing decisions belong with you and your prescriber.

Vial sizes and syringe math are in the Oxandrolone guide.

Frequently asked questions

When does oxandrolone peak after a dose?+
We could not confirm a published time to peak for oxandrolone, so we do not give one. Individual timing varies with food, the amount and the person.
How long does oxandrolone take to reach steady state?+
About 2.2 days of regular dosing at the same amount and interval, which is 5 half-lives. With a half-life of about 10.4 hours, levels reach about 50% of steady state after 10.4 hours and about 90% after 34.5 hours. Changing the dose or interval starts a new climb toward a new steady state.
Does splitting oxandrolone into more frequent doses keep levels steadier?+
In the model, it narrows the swing but not the average. With the same total per week, the peak-to-trough ratio at steady state is about 2.07:1 every 0.5 days, about 4.57:1 daily. Which schedule to use is a decision for you and your prescriber.
How long does oxandrolone stay in your system after the last dose?+
Roughly 5 half-lives, about 2.2 days, until about 97% has cleared in the model. Half is gone about 10.4 hours after levels start falling. Real clearance varies from person to person, and a drug can still have effects after levels are low.
Is this chart my actual oxandrolone level?+
No. It is a modeled estimate from a published half-life, using the same one-compartment model as the Dose Track app. Real levels vary with body weight, food, kidney and liver function and other factors, and only a lab test measures them. It is not medical advice.