Short answer: Oxandrolone has a half-life of about 10.4 hours (Oxandrin (oxandrolone tablets, USP) label) and reaches steady state after about 2.2 days of regular dosing. We could not confirm a published time to peak for oxandrolone, so we do not state one. With the same total per week, Dose Track's model gives a peak-to-trough swing of about 2.07:1 every 0.5 days and about 4.57:1 daily.
The former Oxandrin label gave adults 2.5 to 20 mg a day, split into 2 to 4 doses, for 2 to 4 weeks at a time. The chart compares 10 mg once daily with 5 mg twice daily. US approval has been withdrawn. Source: Oxandrin (oxandrolone tablets, USP) label. Bioavailability 97% as in the app. Dashed line: 5 half-lives. Change the amount or schedule in the calculator.
We could not confirm a published time to peak for oxandrolone, so we do not state one. The curve still needs a rise time, so it uses the app's modeling estimate; treat the shape of the first day or two as approximate.
With regular dosing at a fixed amount and interval, levels climb toward steady state by the same fraction every half-life, whatever the dose. At a half-life of about 10.4 hours:
| Share of steady state | Half-lives | Time |
|---|---|---|
| 50% | 1 | 10.4 hours |
| 75% | 2 | 20.8 hours |
| 90% | 3.3 | 34.5 hours |
| 97% (Dose Track's steady-state rule) | 5 | 2.2 days |
The longer the gap between doses compared with the half-life, the bigger the swing from peak to trough and the less the levels build up. These ratios do not depend on the amount.
| Interval | Peak : trough | Build-up vs one dose |
|---|---|---|
| Daily | 4.57 : 1 | 1.25× |
| Every other day | 22.6 : 1 | 1.04× |
| Twice weekly | 249 : 1 | 1× |
| Weekly | over 1,000 : 1 | 1× |
| Every 2 weeks | over 1,000 : 1 | 1× |
Build-up is the accumulation ratio 1 / (1 − e−k·τ), with k = ln 2 / half-life and τ the interval.
After the last dose, about half is gone every 10 hours. After 5 half-lives, about 2.2 days, roughly 97% has cleared in the model.
The former Oxandrin label reports a mean elimination half-life of 10.4 hours in younger volunteers and 13.3 hours in elderly volunteers; Dose Track uses 10.4 hours, the figure for younger adults. The label gives no time to peak, so we do not list one.
The curve uses the half-life, time to peak, route and bioavailability built into the Dose Track app for oxandrolone, and the same one-compartment model with first-order absorption. These are modeled estimates from published half-lives, drawn with the same one-compartment model as the Dose Track app. Real levels vary from person to person, and only a lab test measures them. This is not medical advice and not a dosing recommendation; dosing decisions belong with you and your prescriber.
Vial sizes and syringe math are in the Oxandrolone guide.
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