Short answer: For male hypogonadism, the testosterone enanthate label suggests 50 to 400 mg every 2 to 4 weeks, injected slowly and deep into the gluteal muscle. It says total doses above 400 mg per month are generally not required and injections more often than every two weeks are rarely indicated. Delayed puberty is 50 to 200 mg every 2 to 4 weeks for a limited time.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Testosterone enanthate is approved for: In males, testosterone enanthate injection is approved as replacement for low or absent natural testosterone from primary hypogonadism or hypogonadotropic hypogonadism, and to stimulate puberty in carefully selected males with clearly delayed puberty. In women it may be used secondarily for advancing inoperable metastatic breast cancer one to five years after menopause. Safety and effectiveness in men with age-related hypogonadism have not been established (Indications and Usage).
Source
Testosterone enanthate injection, USP, prescribing information. Hikma. DailyMed, version published May 11, 2026. DailyMed setid e89d6458-428c-4256-97a3-f1fa851293c1
Testosterone enanthate is injected slowly and deeply into the gluteal (buttock) muscle, following the usual precautions for intramuscular injections, such as avoiding a blood vessel (Dosage and Administration).
The label notes that a wet needle or syringe can make the solution cloudy without changing its strength. It is a clear, colorless to pale yellow solution.
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Use | Dose on the label | How often | Notes |
|---|---|---|---|
| Male hypogonadism (replacement therapy) | 50 to 400 mg | Every 2 to 4 weeks | Suggested dosage |
| Males with delayed puberty | 50 to 200 mg | Every 2 to 4 weeks | For a limited duration, for example, 4 to 6 months |
| Palliation of inoperable mammary cancer in women | 200 to 400 mg | Every 2 to 4 weeks | Followed closely; androgens occasionally appear to speed the disease |
Before starting, low testosterone is confirmed with morning serum testosterone on at least two separate days, both below the normal range.
Dose and length of treatment depend on age, sex, diagnosis, response to treatment and side effects.
In general, total doses above 400 mg per month are not required because of the long action of the preparation. Injections more often than every two weeks are rarely indicated.
For delayed puberty, some regimens start low and rise as puberty progresses; others start higher and lower for maintenance. Age and bone age guide the dose, with X-rays at intervals.
Hemoglobin and hematocrit are checked periodically with high doses; cholesterol is checked repeatedly and treatment adjusted accordingly.
Blood pressure is monitored periodically, especially in men with high blood pressure.
The testosterone enanthate label gives no missed-dose instruction. Ask your prescriber what to do if an injection is late.
More on this: missed a dose of Testosterone enanthate.
In Dose Track you set up Testosterone enanthate as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.