Short answer: The Azmiro label gives 50 mg to 400 mg every two to four weeks as a deep injection into the buttock (gluteal) muscle. The dose and schedule are set for each person based on age, diagnosis, response and side effects. The prefilled syringe is used only for 200 mg doses and only by a healthcare professional; other doses come from the 200 mg/mL vial.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Azmiro is approved for: Azmiro is approved as testosterone replacement therapy in males with low or absent natural testosterone due to primary hypogonadism (testicular failure) or hypogonadotropic hypogonadism (a pituitary or hypothalamus cause). The label says safety and efficacy have not been established in men with "age-related hypogonadism" or in children under 12 (section 1).
Source
AZMIRO (testosterone cypionate) injection, for intramuscular use, CIII, prescribing information and Medication Guide. Azurity Pharmaceuticals. DailyMed, version published July 28, 2025. DailyMed setid 235b5625-570d-3fba-e063-6394a90aa2d1
Azmiro is given only as a deep intramuscular injection in the gluteal (buttock) muscle (section 2.1).
It comes as 200 mg/mL in a 1 mL single-dose vial or a 1 mL single-dose prefilled syringe. Any unused portion of a vial is discarded (sections 2.4, 3).
The prefilled syringe is given only by a healthcare professional and only for 200 mg doses. Its carton has no needle, so a suitable needle is obtained separately (section 2.5).
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Item | What the label says |
|---|---|
| Dose range | 50 mg to 400 mg |
| How often | Every two to four weeks |
| Where | Deep intramuscular injection in the gluteal muscle |
| How the dose is chosen | Individualized based on age, diagnosis, response to treatment and adverse reactions |
| Prefilled syringe | 200 mg doses only, given by a healthcare professional |
| Other doses | Use the Azmiro single-dose vial |
Before starting, hypogonadism is confirmed by morning serum testosterone measured on at least two separate days, with both results below the normal range.
Injectable testosterone products are not substitutable on a milligram-per-milligram basis.
Hematocrit is checked before starting and periodically during treatment.
Prolactin is checked before starting and again 3 to 4 months after.
Prostate cancer, including PSA, is checked before and during treatment; blood pressure and lipids are monitored periodically (sections 5.4, 5.12).
People on blood thinners may need frequent INR and prothrombin time checks, especially when starting and stopping testosterone.
The Azmiro label gives no missed-dose instruction. It describes injections every two to four weeks given by a healthcare provider; ask your prescriber what to do if an injection is late.
More on this: missed a dose of Azmiro.
The label says injectable testosterone products may differ in dose, strength and administration and are not substitutable milligram for milligram. It gives no conversion from other testosterone products.
In Dose Track you set up Azmiro as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.