Short answer: The Xyosted label has no missed-dose instructions. It is a once-weekly autoinjector, and its doses are adjusted from a trough testosterone level drawn 7 days after the most recent dose. So a late dose also shifts the timing of that blood test. Ask your prescriber how to get back on schedule.
| Situation | What the label says |
|---|---|
| Label schedule | Once weekly, under the skin of the abdomen (2.2) |
| Missed-dose rule | None in the label |
| Dose adjustment | Based on trough total testosterone 7 days after the last dose (2.2) |
| Device | Single-dose autoinjector; discard any unused portion (2.3) |
No. The Xyosted prescribing information and Medication Guide on DailyMed give no missed-dose or catch-up instructions. In the 52-week trial, patients were taught to inject once weekly on the same day of the week and at about the same time (section 14).
Section 2.2 bases dose changes on a total testosterone trough level measured 7 days after the most recent dose: after 6 weeks of dosing, 6 weeks after any dose change, and periodically after that. If a dose was late, a blood draw scheduled for "7 days after" needs to count from the real injection date, or the result will not mean what it is supposed to.
Each autoinjector is a single weekly dose, and the label does not describe giving two in a short span. Talk to your prescriber rather than doubling up.
The label does not cover changing the weekly day. Since dose decisions depend on a trough drawn 7 days after a dose, let your prescriber know if your day moves.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.