Short answer: Neither the Egrifta WR nor the Egrifta SV label gives missed-dose instructions. Both are once-daily injections, and tesamorelin has a half-life of about 8 to 11 minutes. The labels set no catch-up dose, so do not double up without asking. Note that an Egrifta WR vial must be thrown away 7 days after mixing, missed days or not.
| Situation | What the label says |
|---|---|
| Egrifta WR schedule | 1.28 mg once daily (2.1) |
| Egrifta SV schedule | 1.4 mg once daily (2.1) |
| Missed-dose rule | None in either label |
| Egrifta WR mixed vial | 7 daily doses; discard 7 days after mixing (2.2) |
| Egrifta SV mixed vial | Use immediately; discard unused solution (2.2) |
No. We checked the Egrifta WR and Egrifta SV prescribing information and patient information on DailyMed. Neither has a missed-dose instruction. Both are dosed once daily: Egrifta WR at 1.28 mg and Egrifta SV at 1.4 mg (section 2.1 of each).
One mixed Egrifta WR vial provides daily doses for 7 days, and section 2.2 says to discard unused solution 7 days after mixing. A missed day does not extend that. The leftover dose in the vial is thrown away on day 7, not carried over.
Egrifta SV is different: each vial is mixed and used right away, and any unused solution is thrown away (section 2.2). A missed day leaves an unopened vial for the next dose.
Tesamorelin has a mean elimination half-life of about 11 minutes for Egrifta WR and 8 minutes for Egrifta SV (section 12.3). It works by prompting the body to release its own growth hormone, so each dose acts on the day it is given. A second dose later does not replace the missed day.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.