Short answer: The Azmiro label has no missed-dose instructions. It gives 50 to 400 mg every 2 to 4 weeks, injected deep into the gluteal muscle, and a half-life of approximately eight days. So a few days late lowers levels gradually, not suddenly. Ask your prescriber whether to inject now or wait for your next scheduled day.
| Situation | What the label says |
|---|---|
| Label schedule | 50 to 400 mg every 2 to 4 weeks, deep in the gluteal muscle (2.3) |
| Missed-dose rule | None in the label |
| Half-life (IM) | Approximately eight days (12.3) |
| Prefilled syringe | 200 mg doses only, given by a healthcare professional (2.5) |
No. We checked the Azmiro prescribing information and Medication Guide on DailyMed. Neither has a missed-dose or catch-up instruction.
Section 2.3 gives 50 mg to 400 mg every two to four weeks as a deep intramuscular injection in the gluteal muscle. The dose and schedule are set by age, diagnosis, response to treatment and side effects.
Section 12.3 gives the half-life of Azmiro injected into the muscle as approximately eight days. It explains that testosterone esters in oil are absorbed slowly, which is why Azmiro can be given two to four weeks apart. After a single 200 mg dose in the label's study, the median time to the peak level was 71.7 hours.
With a half-life that long, a shot a few days late means a few days lower in your usual range, not a sudden drop.
Section 2.5 says the prefilled syringe is given as an intramuscular injection by a healthcare professional only, and only for 200 mg doses. Other doses use the single-dose vial, and any drug left in the vial is discarded (section 2.4). If your shots are given at a clinic, the clinic decides how to reschedule a missed one; the label gives no timing rule.
The label does not describe catch-up doses or set a minimum gap. Section 5.1 says hematocrit is checked before starting and periodically during treatment, and Azmiro is stopped if it becomes elevated. Doubling up raises the peak level. Ask your prescriber before changing the amount or the spacing.
It can. Testosterone results depend on how many days have passed since the last injection, so the real date of a late shot matters to whoever reads your labs.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.