How to Store Novarel hCG: Before and After Mixing
[Storage · Novarel]

How to store Novarel (hCG)

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Store the unmixed Novarel powder at room temperature, 68-77°F (20-25°C). Once you mix it with the bacteriostatic water it comes with, the label says: refrigerate at 36-46°F (2-8°C) and use within 30 days. That 30-day figure is Novarel's; Pregnyl's label gives 60 days. Source: Novarel label, Storage and Description sections.

What does the Novarel label say?

Novarel (chorionic gonadotropin for injection) US label.
StageStorageLimit
Unmixed powder68-77°F (20-25°C); excursions 59-86°F (15-30°C)Until the expiration date
MixedRefrigerate at 36-46°F (2-8°C)Use within 30 days

Storage section, in capitals on the label: “REFRIGERATE RECONSTITUTED PRODUCT AT 2° to 8°C (36° to 46°F) AND USE WITHIN 30 DAYS.” The Description section adds that when mixed with bacteriostatic water preserved with 0.9% benzyl alcohol, “the solution should be refrigerated and used within 30 days.”

Does the water I mix Novarel with matter?

Yes. Novarel comes as 5,000 or 10,000 unit multiple-dose vials with a 10 mL vial of Bacteriostatic Water for Injection with 0.9% benzyl alcohol. The 30 days is tied to mixing with that diluent. The label does not give a figure for other liquids. See bacteriostatic vs sterile water.

Dose and unit math for hCG is on the hCG page and the reconstitution calculator.

What if mixed Novarel was left out or froze?

The Novarel label gives no room-temperature allowance for the mixed solution and no instruction for freezing. Ask your pharmacist or fertility clinic about a vial that spent time outside the fridge.

How do you travel with it?

Unmixed Novarel can travel at room temperature. Once mixed, keep it cold in an insulated bag with a cold pack that does not touch the vial.

  • TSA allows medically necessary liquids over 3.4 oz in carry-on bags; declare them at the checkpoint for inspection.
  • Unused syringes and pen needles are allowed when they travel with the injectable medicine.
  • Ice packs and gel packs that keep medicine cool may go through frozen, partly frozen or melted.
  • Keep medicine in your carry-on, not checked luggage, where you cannot control the temperature. Do not let it touch an ice pack directly, since most labels say do not freeze.

More in the travel guide.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.

Frequently asked questions

How long is Novarel good after mixing?+
Refrigerate at 36-46°F (2-8°C) and use within 30 days, per the Novarel label.
Does unmixed Novarel need to be refrigerated?+
No. Store the powder at 68-77°F (20-25°C).
Why does Pregnyl say 60 days and Novarel 30?+
Each figure comes from that product's own testing. Use the number on the label of the product you have.