[TRT · Compound guide]

hCG (Human Chorionic Gonadotropin): reconstitution, units and half-life

Vial sizes · Worked example · Units chart · Half-life ~29 hours

What is hCG?

Human chorionic gonadotropin (hCG) is a hormone that acts on the same receptor as luteinizing hormone (LH). Novarel and Pregnyl are powder vials that are mixed before use; Ovidrel is a pre-filled syringe.

Also known as: Novarel, Pregnyl, Ovidrel, chorionic gonadotropin.

Common vial sizes

Novarel comes in 5,000 and 10,000 unit vials. Labels say "USP units", which are the same as the international units (IU) most people use.

Worked reconstitution example

Here is the math for a 5,000 IU vial mixed with 5 mL of bacteriostatic water, drawing 500 IU with a U-100 insulin syringe (1 mL = 100 units).

  1. Concentration. 5,000 IU ÷ 5 mL = 1,000 IU/mL
  2. Volume to draw. 500 IU ÷ 1,000 IU/mL = 0.5 mL
  3. Syringe units. 0.5 mL × 100 = 50 units
The amount here is an example to show the math, not a recommendation. How much to take is a decision for you and your prescriber.

Units chart at 1,000 IU/mL

5,000 IU vial + 5 mL water. Amounts are examples for the conversion, not doses.
AmountVolumeU-100 syringe
250 IU0.25 mL25 units
500 IU0.5 mL50 units
1,000 IU1 mL100 units

Same amount, different water volumes

Adding more water doesn't change how much hCG is in the vial. It only spreads it over more liquid, so each draw is bigger and easier to read.

500 IU from a 5,000 IU vial.
Water addedConcentrationVolumeU-100 syringe
1 mL5,000 IU/mL0.1 mL10 units
2 mL2,500 IU/mL0.2 mL20 units
3 mL1,666.7 IU/mL0.3 mL30 units
5 mL1,000 IU/mL0.5 mL50 units

For any other vial size or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.

HCG half-life and time to peak

  • Half-lifeabout 29 hours
  • Time to peak (Tmax)about 20 hours
  • Route in Dose TrackUnder the skin (subcutaneous)

The FDA Ovidrel label reports a terminal half-life of about 29 hours after an injection under the skin, with levels peaking about 12 to 24 hours after the shot. Ovidrel is recombinant hCG studied mostly in women; Novarel and Pregnyl are labeled for injection into muscle, so the Ovidrel figures are the closest label data for an injection under the skin.

Numbers shown are the values Dose Track uses, listed only where they agree with the source above. Half-life varies from person to person and with injection site.

How to track hCG in Dose Track

  1. Add hCG from the built-in list. It sits next to everything else you take, so a GLP-1, TRT and a few peptides all live in one log.
  2. Save your vial: enter the vial size and how much water you added. From then on every amount you log shows as syringe units, and the reconstitution planner suggests a water volume that lands on a clean mark.
  3. Log each shot. The app subtracts it from the vial, shows what is left, and warns you before you run out.
  4. Set reminders on your own schedule, whether that is daily, weekly or every few days.
  5. Your log stays on your phone.

Frequently asked questions

How much bacteriostatic water do I add to a 5,000 IU hCG vial?+
There is no single right amount. More water makes each draw bigger and easier to measure; less water makes it smaller. For example, 5 mL in a 5,000 IU vial gives 1,000 IU/mL, so 500 IU is 0.5 mL, or 50 units on a U-100 insulin syringe. That amount is only an example for the math, not a recommendation. The free Dose Track reconstitution calculator works it out for any vial and amount.
How many units is 500 IU of hCG?+
It depends on the concentration in your vial. At 1,000 IU/mL (5,000 IU mixed with 5 mL), 500 IU is 0.5 mL, which is 50 units on a U-100 insulin syringe, where 1 mL is 100 units. Divide the amount by the concentration to get mL, then multiply by 100.
What is the half-life of hCG?+
Dose Track uses a half-life of about 29 hours for hCG. The FDA Ovidrel label reports a terminal half-life of about 29 hours after an injection under the skin, with levels peaking about 12 to 24 hours after the shot. Ovidrel is recombinant hCG studied mostly in women; Novarel and Pregnyl are labeled for injection into muscle, so the Ovidrel figures are the closest label data for an injection under the skin.
Can I track hCG in Dose Track?+
Yes. HCG is built into Dose Track. You can log each shot next to your other compounds, save your vial and how much water you added so every amount shows in syringe units, see how much is left in the vial, and get reminders. Your log stays on your phone.