Abaloparatide is a synthetic analog of parathyroid hormone-related peptide, PTHrP(1-34). It is FDA approved as Tymlos for osteoporosis at high risk of fracture in postmenopausal women and in men.
Also known as: Tymlos.
Tymlos comes in a prefilled pen holding 3,120 mcg in 1.56 mL (2,000 mcg/mL), which delivers 30 daily doses of 80 mcg. There is nothing to mix and no syringe math. The label dose is 80 mcg under the skin of the lower abdomen around the navel once a day.
If you also use a powder peptide, the free peptide reconstitution calculator handles the vial math.
The FDA Tymlos label gives a mean half-life of about 1 hour and a median time to peak of 0.51 hours (about 30 minutes) after an 80 mcg injection under the skin, with bioavailability of 36%.
Numbers shown are taken from the source above. Half-life varies from person to person and with injection site.