[GLP-1 units · Tirzepatide]

How many units is tirzepatide? Every dose at every vial strength

5 vial strengths · U-100 syringe · Reviewed

Short answer: It depends on the strength printed on the vial. 2.5 mg of tirzepatide is 50 units at 5 mg/mL, 31.25 units at 8 mg/mL, 25 units at 10 mg/mL, 16.67 units at 15 mg/mL, 12.5 units at 20 mg/mL on a U-100 insulin syringe. The formula is mg ÷ mg/mL × 100 = units. Units measure volume, so they change whenever the vial strength changes.

Compounded vs FDA-approved. Compounded tirzepatide is not FDA approved, and FDA does not review compounded drugs for safety, effectiveness or quality before they are sold (FDA). Mounjaro and Zepbound single-dose pens each hold one fixed dose, and the KwikPen is set to its labeled dose, so the dose is chosen in mg and there are no syringe units to work out. The labeled single-dose vials are one dose each, and the labeled multi-dose vial gives four doses of 0.6 mL; follow the instructions for use that come with them, not a compounded units chart.

How many units is each tirzepatide dose by vial strength?

Rows are the dose steps named in the Mounjaro and Zepbound labels; columns are compounded vial strengths. Each cell is units on a U-100 insulin syringe. Not personalized advice; confirm your dose, in mg and in units, with your prescriber or the dispensing pharmacy.

Tirzepatide mg to U-100 units. Click a strength for its full page.
Dose5 mg/mL8 mg/mL10 mg/mL15 mg/mL20 mg/mL
2.5 mg5031.252516.6712.5
5 mg10062.55033.3325
7.5 mg150 (over 1 mL)93.75755037.5
10 mg200 (over 1 mL)125 (over 1 mL)10066.6750
12.5 mg250 (over 1 mL)156.25 (over 1 mL)125 (over 1 mL)83.3362.5
15 mg300 (over 1 mL)187.5 (over 1 mL)150 (over 1 mL)10075

Cells over 100 units need more than one 1 mL syringe. Non-whole numbers fall between printed marks; see how to read insulin syringe marks.

Which strength is on your vial?

Compounded tirzepatide is dispensed already in solution, at a strength set by the pharmacy. There is no standard; FDA's 2024 alert notes one compounder may offer several concentrations. Pick the page that matches the mg/mL on your label:

What is the FDA label dosing schedule?

Zepbound (FDA label, section 2)

Label schedule, quoted from the prescribing information. Your prescriber sets your own schedule.
WhenLabel dose
Weeks 1 to 42.5 mg once weekly (for starting treatment only)
Week 55 mg once weekly
Further stepsIncrease by 2.5 mg after at least 4 weeks on the current dose
Maintenance5 mg, 10 mg or 15 mg once weekly for weight reduction; 10 mg or 15 mg for obstructive sleep apnea
Maximum15 mg once weekly

The label states that 2.5 mg is for starting treatment and is not an approved maintenance dose.

Mounjaro (FDA label, section 2)

Label schedule, quoted from the prescribing information. Your prescriber sets your own schedule.
WhenLabel dose
Start2.5 mg once weekly
Further stepsIf more glycemic control is needed, increase by 2.5 mg after at least 4 weeks on the current dose
Maximum15 mg once weekly in adults

For pediatric patients 10 years and older the Mounjaro label sets a lower maximum of 10 mg once weekly.

Why do unit mix-ups happen?

FDA has received reports of overdoses, some needing hospital care, from compounded semaglutide in multi-dose vials. In the reports, patients drew more than the prescribed amount, and some prescribers miscalculated the conversion from mg to units; FDA links the errors to confusion between milligrams, milliliters and units. One example FDA gives: a 0.25 mg dose meant to be 5 units was prescribed as 25 units. The insulin syringe guide covers the syringe side of the problem.

Related: Semaglutide units by strength · Tirzepatide guide and powder vials · Ozempic vs Mounjaro

Frequently asked questions

How many units is 2.5 mg of tirzepatide?+
It depends on the strength of the vial. At 5 mg/mL it is 50 units; At 8 mg/mL it is 31.25 units; At 10 mg/mL it is 25 units; At 15 mg/mL it is 16.67 units; At 20 mg/mL it is 12.5 units (U-100 insulin syringe). Divide the mg by the mg/mL on the vial, then multiply by 100. Not personalized advice; confirm your dose, in mg and in units, with your prescriber or the dispensing pharmacy.
Why do different pharmacies give different units for the same tirzepatide dose?+
Compounded tirzepatide has no standard strength, and FDA notes that one compounder may offer several concentrations. Units measure volume, not drug, so the same mg is more units in a weaker vial and fewer units in a stronger one. Recheck the units whenever the strength on the label changes.
Do Mounjaro and Zepbound pens need units?+
Mounjaro and Zepbound single-dose pens each hold one fixed dose, and the KwikPen is set to its labeled dose, so the dose is chosen in mg and there are no syringe units to work out. The labeled single-dose vials are one dose each, and the labeled multi-dose vial gives four doses of 0.6 mL; follow the instructions for use that come with them, not a compounded units chart.
What dose steps are in the Mounjaro and Zepbound labels?+
The labels name these steps: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg. Each label sets its own schedule and maximum; see the schedule section on this page. Compounded products have no FDA label.