How many units is 0.25 mg of semaglutide?

It depends on the strength of the vial. At 1 mg/mL it is 25 units; At 2 mg/mL it is 12.5 units; At 2.5 mg/mL it is 10 units; At 5 mg/mL it is 5 units (U-100 insulin syringe). Divide the mg by the mg/mL on the vial, then multiply by 100. Not personalized advice; confirm your dose, in mg and in units, with your prescriber or the dispensing pharmacy.

Why do different pharmacies give different units for the same semaglutide dose?

Compounded semaglutide has no standard strength, and FDA notes that one compounder may offer several concentrations. Units measure volume, not drug, so the same mg is more units in a weaker vial and fewer units in a stronger one. Recheck the units whenever the strength on the label changes.

What dose steps are in the Ozempic and Wegovy labels?

The labels name these steps: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2 mg, 2.4 mg, 7.2 mg. Each label sets its own schedule and maximum; see the schedule section on this page. Compounded products have no FDA label.

How Many Units Is Semaglutide? Chart by mg/mL

Short answer: It depends on the strength printed on the vial. 0.25 mg of semaglutide is 25 units at 1 mg/mL, 12.5 units at 2 mg/mL, 10 units at 2.5 mg/mL, 5 units at 5 mg/mL on a U-100 insulin syringe. The formula is mg ÷ mg/mL × 100 = units. Units measure volume, so they change whenever the vial strength changes.

Compounded vs FDA-approved. Compounded semaglutide is not FDA approved, and FDA does not review compounded drugs for safety, effectiveness or quality before they are sold (FDA). Ozempic pens are set to deliver 0.25, 0.5, 1 or 2 mg, and Wegovy single-dose pens each hold one fixed dose, so the dose is chosen in mg and there are no syringe units to work out.

How many units is each semaglutide dose by vial strength?

Rows are the dose steps named in the Ozempic and Wegovy labels; columns are compounded vial strengths. Each cell is units on a U-100 insulin syringe. Not personalized advice; confirm your dose, in mg and in units, with your prescriber or the dispensing pharmacy.

Semaglutide mg to U-100 units. Click a strength for its full page.
Dose	1 mg/mL	2 mg/mL	2.5 mg/mL	5 mg/mL
0.25 mg	25	12.5	10	5
0.5 mg	50	25	20	10
1 mg	100	50	40	20
1.7 mg	170 (over 1 mL)	85	68	34
2 mg	200 (over 1 mL)	100	80	40
2.4 mg	240 (over 1 mL)	120 (over 1 mL)	96	48
7.2 mg	720 (over 1 mL)	360 (over 1 mL)	288 (over 1 mL)	144 (over 1 mL)

Cells over 100 units need more than one 1 mL syringe. Non-whole numbers fall between printed marks; see how to read insulin syringe marks.

Which strength is on your vial?

Compounded semaglutide is dispensed already in solution, at a strength set by the pharmacy. There is no standard; FDA's 2024 alert notes one compounder may offer several concentrations. Pick the page that matches the mg/mL on your label:

What is the FDA label dosing schedule?

Wegovy injection (FDA label, Table 1)

Label schedule, quoted from the prescribing information. Your prescriber sets your own schedule.
When	Label dose
Weeks 1 to 4	0.25 mg once weekly
Weeks 5 to 8	0.5 mg once weekly
Weeks 9 to 12	1 mg once weekly
Weeks 13 to 16	1.7 mg once weekly
Week 17 onward	Maintenance: 1.7 mg or 2.4 mg once weekly (2.4 mg recommended for adult weight reduction)

For adult weight reduction, the label allows patients who have tolerated 2.4 mg for at least 4 weeks to increase to a maximum of 7.2 mg once weekly. If a dose is not tolerated during escalation, the label says to consider delaying escalation for 4 weeks.

Ozempic (FDA label, section 2)

Label schedule, quoted from the prescribing information. Your prescriber sets your own schedule.
When	Label dose
First 4 weeks	0.25 mg once weekly
After 4 weeks	0.5 mg once weekly
After at least 4 more weeks, if needed	1 mg once weekly
After at least 4 more weeks, if needed	2 mg once weekly (maximum)

The label describes 0.25 mg as a starting dose. Increases past 0.5 mg are for additional glycemic control.

Why do unit mix-ups happen?

FDA has received reports of overdoses, some needing hospital care, from compounded semaglutide in multi-dose vials. In the reports, patients drew more than the prescribed amount, and some prescribers miscalculated the conversion from mg to units; FDA links the errors to confusion between milligrams, milliliters and units. One example FDA gives: a 0.25 mg dose meant to be 5 units was prescribed as 25 units. The insulin syringe guide covers the syringe side of the problem.

How many units is semaglutide? Every dose at every vial strength