HbA1c (A1C) Explained: Your 3-Month Blood Sugar
[Glossary · How doses act in the body]

HbA1c (hemoglobin A1C)

Also called A1C, HbA1c, hemoglobin A1c, glycated hemoglobin, glycohemoglobin · Reviewed

Definition: HbA1c, or A1C, is a blood test that shows your average blood sugar over the past two to three months. Sugar in the blood sticks to hemoglobin in red blood cells, and the test measures the percentage of hemoglobin coated with sugar. Red blood cells live about three months, which sets the time window.

The diagnosis cutoffs

A1C ranges used to diagnose prediabetes and diabetes (CDC and MedlinePlus).
ResultMeaning
Below 5.7%Normal
5.7% to 6.4%Prediabetes
6.5% or aboveDiabetes

MedlinePlus says these ranges are a guide, and that providers often confirm a high result with a second test. The CDC says you do not need to fast for an A1C test.

Why it shows up when you track doses

A1C is the main blood sugar result in the diabetes trials on GLP-1 drug labels. The Ozempic label reports that semaglutide lowered HbA1c compared with placebo in adults with type 2 diabetes, and the Mounjaro label uses HbA1c the same way for tirzepatide. The CDC says most people with diabetes have A1C tested at least twice a year.

The CDC says a home glucose check is a snapshot of one moment, while A1C is a three-month average, so the two answer different questions. A1C does not replace home monitoring.

What can throw it off

The CDC lists severe anemia, kidney failure, liver disease, blood disorders such as sickle cell anemia, blood loss or transfusions, early or late pregnancy, and certain medicines including opioids and some HIV drugs. Tell your provider if any apply.

Read more on Dose Track: Blood sugar · Semaglutide guide · Logging lab results in Dose Track

General education drawn from labels and published studies, not personal medical advice. Your prescriber, pharmacist and the label that came with your product are the final word.

Frequently asked questions

Do I need to fast for an A1C test?+
No. The CDC says fasting is not needed, though other tests drawn at the same visit, such as cholesterol, may need it.
How often is A1C checked?+
The CDC says most people with diabetes have it tested at least twice a year, and people with prediabetes about every 1 to 2 years. Your clinician sets your schedule.
Why did my A1C not change after a few weeks?+
A1C reflects about three months of blood sugar because red blood cells live about that long, so it changes slowly.