HDL Cholesterol: Healthy Levels and What Lowers It
[Glossary · How doses act in the body]

HDL cholesterol

Also called HDL, HDL-C, high-density lipoprotein, good cholesterol · Reviewed

Definition: HDL cholesterol is cholesterol carried by high-density lipoproteins. MedlinePlus calls it the "good" cholesterol because it carries cholesterol from other parts of the body back to the liver, which removes it. Unlike LDL, a higher HDL is better, because a high level can lower the risk of coronary artery disease and stroke.

Healthy levels

Healthy HDL levels, as MedlinePlus gives them
GroupHealthy HDL
Age 19 or youngerMore than 45 mg/dL
Men 20 or olderMore than 40 mg/dL
Women 20 or olderMore than 50 mg/dL

HDL is one line of a standard lipid panel, next to LDL, total cholesterol and triglycerides. MedlinePlus says adults 20 and older are usually tested every 5 years, and more often (every 1 to 2 years) for men 45 to 65 and women 55 to 65. It also lists low HDL with high triglycerides as a risk factor for type 2 diabetes, and says diabetes itself can lower HDL.

Medicines that can lower it

MedlinePlus names anabolic steroids, including testosterone; progestins in some birth control and menopause hormone therapy; beta blockers; and benzodiazepines. Testosterone labels such as AndroGel say blood fats can change and the lipid profile is checked periodically, especially after starting. MedlinePlus adds that some statins can raise HDL, though medicines are not usually prescribed only to raise it.

Why it matters for your log

An HDL drop on testosterone or another hormone is easy to see when each lipid panel sits next to the dose and start date. Noting whether the draw was fasting, and any change in exercise, weight, smoking or alcohol in the weeks before, also helps when results are compared, because MedlinePlus names all of these as things that move HDL.

Read more on Dose Track: Does TRT affect cholesterol? · Cholesterol · AndroGel side effects

General education drawn from labels and published studies, not personal medical advice. Your prescriber, pharmacist and the label that came with your product are the final word.

Frequently asked questions

What is a good HDL level?+
MedlinePlus gives more than 40 mg/dL for men 20 and older, more than 50 mg/dL for women 20 and older, and more than 45 mg/dL for people 19 and younger.
Can testosterone lower HDL?+
MedlinePlus lists anabolic steroids, including testosterone, among medicines that can lower HDL, and testosterone labels say the lipid profile is checked periodically.