Heart Attack (Myocardial Infarction) on Drug Labels
[Glossary · How doses act in the body]

Heart attack

Also called myocardial infarction, MI, nonfatal myocardial infarction · Reviewed

Definition: A heart attack, also called a myocardial infarction (MI), happens when blood flow to part of the heart muscle is suddenly blocked, so the muscle does not get enough oxygen. NHLBI says that if blood flow is not restored quickly, the muscle begins to die. It is a medical emergency: anyone who may be having one should call 911 right away.

What to know

MedlinePlus says the most common cause is coronary artery disease, where plaque builds up in the heart's arteries, breaks open and a clot blocks the artery. Common signs are chest discomfort, shortness of breath and pain in the arms, back, neck, jaw or upper stomach, and women more often have other symptoms such as unusual tiredness. A heart attack is not the same as cardiac arrest, when the heart stops beating, though one can trigger the other. NHLBI cites the CDC figure of more than 800,000 heart attacks a year in the US.

How labels use it

  • Heart outcome trials count "nonfatal myocardial infarction" as one part of major adverse cardiovascular events (see cardiovascular outcomes trial). Labels such as Victoza, Repatha and Praluent are approved to lower that risk in named groups.
  • The Cialis label says it is not recommended within 90 days of a heart attack, and must never be taken with nitrates, a heart medicine.
  • The Epogen boxed warning says aiming for a hemoglobin above 11 g/dL in kidney disease raised the risk of serious heart events and death.

Why it matters for your log

The date of any past heart attack decides what some labels allow. Keeping it in your health notes, with your medicine list, means it is ready when a new prescription is discussed.

Read more on Dose Track: Do GLP-1 medicines lower heart attack risk? · Cialis side effects · Repatha side effects · Cholesterol

General education drawn from labels and published studies, not personal medical advice. Your prescriber, pharmacist and the label that came with your product are the final word.

Frequently asked questions

Is a heart attack the same as cardiac arrest?+
No. MedlinePlus says in a heart attack blood flow to the heart is blocked, while in cardiac arrest the heart stops beating. A heart attack can trigger cardiac arrest, and both are emergencies.
What does myocardial infarction mean on a label?+
It is the medical name for a heart attack. Trials count nonfatal myocardial infarction as one of the major heart events they measure.