Humanin is a small peptide encoded in mitochondrial DNA, one of the mitochondrial-derived peptides like MOTS-c. It has been studied in cells and animals; it has not been tested as a treatment in people and is not FDA approved.
Also known as: HN.
Powder vials are usually labeled 10 mg.
Water and syringe-unit charts by vial size: 10 mg
Here is the math for a 10 mg vial mixed with 2 mL of bacteriostatic water, drawing 1 mg with a U-100 insulin syringe (1 mL = 100 units).
10 mg ÷ 2 mL = 5 mg/mL1 mg ÷ 5 mg/mL = 0.2 mL0.2 mL × 100 = 20 units| Amount | Volume | U-100 syringe |
|---|---|---|
| 500 mcg | 0.1 mL | 10 units |
| 1 mg | 0.2 mL | 20 units |
| 2 mg | 0.4 mL | 40 units |
Adding more water doesn't change how much humanin is in the vial. It only spreads it over more liquid, so each draw is bigger and easier to read.
| Water added | Concentration | Volume | U-100 syringe |
|---|---|---|---|
| 1 mL | 10 mg/mL | 0.1 mL | 10 units |
| 2 mL | 5 mg/mL | 0.2 mL | 20 units |
| 3 mL | 3.33 mg/mL | 0.3 mL | 30 units |
| 5 mL | 2 mg/mL | 0.5 mL | 50 units |
For any other vial size or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.
Human research mostly measures the body's own humanin levels. A 2023 systematic review describes protective effects on mitochondria and cells in lab and animal work. We could not find a trial that gave humanin to people.
We could not find a published human half-life for this compound. Figures quoted online usually come from animal or cell studies, so we do not list one here.