How to Store Glyxambi, Trijardy XR, Steglujan, Segluromet
[Storage · Glyxambi, Trijardy XR, Steglujan and Segluromet]

How to store Glyxambi, Trijardy XR, Steglujan and Segluromet

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: All four labels say store at 68°F to 77°F (20°C to 25°C), with excursions allowed to 59°F to 86°F (15°C to 30°C). Trijardy XR adds protect from high humidity; Steglujan and Segluromet add protect from moisture and store in a dry place. Glyxambi gives only the temperature, plus a tight container if repackaged. None gives a fridge instruction.

What do the four labels say?

Glyxambi combines empagliflozin and linagliptin, and Trijardy XR adds extended-release metformin to the same two (Boehringer Ingelheim). Steglujan combines ertugliflozin and sitagliptin, and Segluromet combines ertugliflozin and metformin (Merck).

Glyxambi, Trijardy XR, Steglujan and Segluromet US prescribing information, section 16, and Medication Guides.
ProductSection 16Medication GuideOther
Glyxambi20°C to 25°C (68°F to 77°F); excursions 15°C to 30°C (59°F to 86°F)Room temperature between 68°F to 77°F (20°C to 25°C)If repackaging is required, dispense in a tight container
Trijardy XR20°C to 25°C (68°F to 77°F); excursions 15°C to 30°C (59°F to 86°F). Protect from exposure to high humidity.Room temperature between 68°F to 77°F (20°C to 25°C). Keep tablets dry.Light and container not stated
Steglujan20°C-25°C (68°F-77°F); excursions between 15°C-30°C (between 59°F-86°F). Protect from moisture. Store in a dry place.Room temperature between 68°F to 77°F (20°C to 25°C). Keep Steglujan dry.Unit-of-use bottles of 30 or 90
Segluromet20°C-25°C (68°F-77°F); excursions between 15°C-30°C (between 59°F-86°F). Protect from moisture. Store in a dry place.Room temperature between 68°F to 77°F (20°C to 25°C). Keep Segluromet dry.Unit-of-use bottles of 60 or 180

Which ones need to be kept dry?

Three of the four. Trijardy XR section 16 ends “Protect from exposure to high humidity,” and its Medication Guide says “Keep TRIJARDY XR tablets dry.” Steglujan and Segluromet section 16 both end “Protect from moisture. Store in a dry place,” and their Medication Guides say keep the tablets dry.

Glyxambi section 16 gives only the temperature: “Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].” It also tells pharmacists: “If repackaging is required, dispense in a tight container as defined in USP.” Moisture and light are not stated.

The single-ingredient and two-drug versions are on the Jardiance, Farxiga, Invokana and Steglatro page and the Synjardy, Xigduo XR and Invokamet page.

Dosing and comparisons

Dosing: Glyxambi, Trijardy XR, Steglujan and Segluromet. Missed a dose: Glyxambi, Trijardy XR, Steglujan, Segluromet. Comparisons: Trijardy XR vs Glyxambi, Steglujan vs Glyxambi, Glyxambi vs Janumet, Segluromet vs Synjardy and Steglatro vs Segluromet.

How do you travel with them?

No ice pack is needed. Keep tablets in the closed bottle in your carry-on, within 59°F to 86°F (15°C to 30°C), and out of a hot car. For Trijardy XR, Steglujan and Segluromet, keep the bottle closed and away from a steamy bathroom.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.

Frequently asked questions

Does Glyxambi need to be refrigerated?+
The label gives no fridge instruction. It says store at 20°C to 25°C (68°F to 77°F), with excursions permitted to 15°C to 30°C (59°F to 86°F).
Does Trijardy XR need to be kept dry?+
Yes. Section 16 says protect from exposure to high humidity, and the Medication Guide says keep Trijardy XR tablets dry.
How should Steglujan and Segluromet be stored?+
At 20°C-25°C (68°F-77°F), with excursions permitted between 15°C-30°C (59°F-86°F). Both labels say protect from moisture and store in a dry place.