Short answer: Section 2.5 of the Segluromet label says a missed dose is taken as soon as possible, without doubling up the next dose. The Medication Guide adds: if it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Segluromet is taken twice a day with meals.
| Situation | What the label says |
|---|---|
| Schedule | Twice daily with meals, raised gradually; up to 7.5 mg ertugliflozin/1,000 mg metformin twice daily (2.2) |
| Missed a dose | Take it as soon as possible (2.5) |
| Almost time for the next dose | Skip the missed dose; take the next at the regular time (Medication Guide) |
| Doubling up | Do not double up the next dose (2.5); do not take 2 doses at the same time (Medication Guide) |
| Planned pause | Held at least 4 days, if possible, before surgery or procedures with long fasting (2.4) |
Section 2.5, Recommendations Regarding Missed Dose: "If a dose is missed, instruct patients to take the dose as soon as possible. Advise patients not to double up the next dose."
Section 17 says: "If a dose is missed, it should be taken as soon as the patient remembers. Advise patients not to double their next dose."
The Medication Guide says: "If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take 2 doses of SEGLUROMET at the same time. Talk with your healthcare provider if you have questions about a missed dose."
The missed-dose wording does not say. Section 2.2 says Segluromet is taken twice daily with meals, with the dose raised gradually.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.