Short answer: If there are at least 3 days (72 hours) until your next scheduled dose, the Trulicity label says to take the missed dose as soon as possible. If fewer than 3 days remain, skip it and take the next dose on your usual day. Do not take two doses within 3 days of each other.
| Situation | What the label says |
|---|---|
| Schedule | Once weekly |
| 3 or more days until the next dose | Take the missed dose as soon as possible (2.3) |
| Less than 3 days until the next dose | Skip it; take the next dose on the usual day (2.3) |
| Minimum time between doses | 3 days (72 hours) (2.3, Medication Guide) |
| Several weeks missed | No specific rule in the Trulicity label |
| Changing your injection day | Allowed if the last dose was 3 or more days before (2.3) |
Section 2.3 of the Trulicity prescribing information says to take the missed dose as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose. Then resume your usual weekly day.
Like Wegovy, the Trulicity rule counts forward to the next dose instead of back from the missed one. With a weekly schedule, it works out to about 4 days of leeway after the missed day.
Skip the missed dose and take the next one on your regularly scheduled day. Section 17 of the label phrases it as: if the next dose is due in 1 or 2 days, do not take the missed dose.
No. The Medication Guide says not to take 2 doses of Trulicity within 3 days of each other.
The Trulicity label does not give a separate rule for restarting after several missed weeks. Whether to resume your usual dose or restart at a lower one is a question for your prescriber, especially if stomach side effects were a problem when you first started.
Dulaglutide has an elimination half-life of about 5 days (label section 12.3).
Yes, if needed, as long as the last dose was given 3 or more days before the new day, per section 2.3.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.