How many units is 0.25 mg of semaglutide at 2.5 mg/mL?

0.25 mg ÷ 2.5 mg/mL = 0.1 mL, which is 10 units on a U-100 insulin syringe (1 mL = 100 units). At a different strength the same mg is a different number of units, so check the strength printed on your vial. Not personalized advice; confirm your dose, in mg and in units, with your prescriber or the dispensing pharmacy.

How many units is each semaglutide label dose at 2.5 mg/mL?

0.25 mg = 10 units; 0.5 mg = 20 units; 1 mg = 40 units; 1.7 mg = 68 units; 2 mg = 80 units; 2.4 mg = 96 units; 7.2 mg = 288 units. These are the dose steps named in the Ozempic and Wegovy labels, converted at 2.5 mg/mL on a U-100 syringe. Doses over 100 units need more than one 1 mL syringe.

How many doses are in a 2 mL vial of semaglutide at 2.5 mg/mL?

A 2 mL vial at 2.5 mg/mL holds 5 mg in total. That is 20 doses of 0.25 mg, 10 doses of 0.5 mg, 5 doses of 1 mg, 2 doses of 1.7 mg. In practice a little is lost to syringe dead space and the last drops in the vial.

Which syringe is used to measure semaglutide in units?

Unit instructions for compounded GLP-1 vials assume a U-100 insulin syringe, where 1 unit is 0.01 mL. A U-40 syringe, used for some veterinary insulin, has different markings and would give 2.5 times the volume at the same number. FDA has asked prescribers and compounders to give patients a syringe sized for the dose and to show them how to measure it.

Semaglutide 2.5 mg/mL: Units per Dose Chart

Q: Is compounded semaglutide the same as Ozempic and Wegovy?

No. Ozempic and Wegovy are FDA-approved products dosed in mg from pens (and, for some, labeled vials). Compounded semaglutide is not FDA approved, and FDA does not review compounded drugs for safety, effectiveness or quality before they are marketed. FDA has received reports of dosing errors with compounded semaglutide in multi-dose vials, many involving confusion between mg, mL and units.

Short answer: At 2.5 mg/mL, 0.25 mg of semaglutide is 0.1 mL, which is 10 units on a U-100 insulin syringe. Every 1 mg is 40 units. The units only hold for a vial labeled 2.5 mg/mL; at another strength the same mg is a different number of units.

Compounded vs FDA-approved. Compounded semaglutide is not FDA approved, and FDA does not review compounded drugs for safety, effectiveness or quality before they are sold (FDA). Ozempic pens are set to deliver 0.25, 0.5, 1 or 2 mg, and Wegovy single-dose pens each hold one fixed dose, so the dose is chosen in mg and there are no syringe units to work out.

How many units is each label dose at 2.5 mg/mL?

The rows below are every dose step named in the Ozempic and Wegovy labels, converted at 2.5 mg/mL for a U-100 insulin syringe (1 mL = 100 units). Not personalized advice; confirm your dose, in mg and in units, with your prescriber or the dispensing pharmacy.

Semaglutide 2.5 mg/mL, U-100 insulin syringe.
Dose	Named in label	Volume	U-100 units	Smallest syringe that holds it
0.25 mg	Ozempic, Wegovy: start	0.1 mL	10 units	0.3 mL (30 units)
0.5 mg	Ozempic, Wegovy	0.2 mL	20 units	0.3 mL (30 units)
1 mg	Ozempic, Wegovy	0.4 mL	40 units	0.5 mL (50 units)
1.7 mg	Wegovy	0.68 mL	68 units	1 mL (100 units)
2 mg	Ozempic: max	0.8 mL	80 units	1 mL (100 units)
2.4 mg	Wegovy	0.96 mL	96 units	1 mL (100 units)
7.2 mg	Wegovy: max (adults, weight reduction)	2.88 mL	288 units	More than one 1 mL syringe

"Between marks" means the volume does not land on a printed line, even on a 0.3 mL syringe with half-unit markings. A 1 mL syringe is usually marked every 2 units, so small doses are easier to read on a 0.3 mL or 0.5 mL barrel. See U-40 vs U-100 syringes and how to read the marks.

How many doses are in a vial at 2.5 mg/mL?

The number of doses depends on how much liquid is in the vial, not only the strength. Check the volume on your vial label, then read across. Counts are whole doses; dead space in the syringe and the last drops in the vial usually take a little more.

Whole doses per vial at 2.5 mg/mL. Vial volumes are examples.
Dose	1 mL vial (2.5 mg)	2 mL vial (5 mg)	3 mL vial (7.5 mg)	5 mL vial (12.5 mg)
0.25 mg	10	20	30	50
0.5 mg	5	10	15	25
1 mg	2	5	7	12
1.7 mg	1	2	4	7
2 mg	1	2	3	6
2.4 mg	1	2	3	5
7.2 mg	0	0	1	1

How do you convert mg to units yourself?

Volume. dose in mg ÷ 2.5 mg/mL = mL
Units. mL × 100 = units on a U-100 syringe
Check. units ÷ 100 × 2.5 = mg, which should match the dose on your prescription.

Example: 0.25 mg ÷ 2.5 mg/mL = 0.1 mL = 10 units. If the units on your instructions do not match this math for the strength on your vial, ask the prescriber or pharmacy before injecting.

What is the FDA label dosing schedule for semaglutide?

Compounded semaglutide has no FDA label of its own. For reference, these are the schedules in the FDA labels for Ozempic and Wegovy, which are dosed in mg.

Wegovy injection (FDA label, Table 1)

Label schedule, quoted from the prescribing information. Your prescriber sets your own schedule.
When	Label dose
Weeks 1 to 4	0.25 mg once weekly
Weeks 5 to 8	0.5 mg once weekly
Weeks 9 to 12	1 mg once weekly
Weeks 13 to 16	1.7 mg once weekly
Week 17 onward	Maintenance: 1.7 mg or 2.4 mg once weekly (2.4 mg recommended for adult weight reduction)

For adult weight reduction, the label allows patients who have tolerated 2.4 mg for at least 4 weeks to increase to a maximum of 7.2 mg once weekly. If a dose is not tolerated during escalation, the label says to consider delaying escalation for 4 weeks.

Ozempic (FDA label, section 2)

Label schedule, quoted from the prescribing information. Your prescriber sets your own schedule.
When	Label dose
First 4 weeks	0.25 mg once weekly
After 4 weeks	0.5 mg once weekly
After at least 4 more weeks, if needed	1 mg once weekly
After at least 4 more weeks, if needed	2 mg once weekly (maximum)

The label describes 0.25 mg as a starting dose. Increases past 0.5 mg are for additional glycemic control.

Other semaglutide strengths

Semaglutide 1 mg/mL · Semaglutide 2 mg/mL · Semaglutide 5 mg/mL · All semaglutide strengths in one grid

Mixing a powder vial instead? The semaglutide reconstitution guide and the free reconstitution calculator handle vials you add water to.

How many units is semaglutide at 2.5 mg/mL?