Tirzepatide 60 mg Reconstitution: BAC Water & Units
[GLP-1 · Tirzepatide · 60 mg vial]

Tirzepatide 60 mg reconstitution: how much water and how many units

Water volume chart · Syringe units · Draws per vial

Short answer: 10 mL of bacteriostatic water in a 60 mg tirzepatide vial makes 6 mg/mL. On a U-100 insulin syringe (1 mL = 100 units), every 10 units then holds 600 mcg. More water gives a weaker solution and a bigger draw for the same amount; the amount in the vial stays 60 mg.

Water volume chart for a 60 mg vial

60 mg tirzepatide vial, U-100 insulin syringe.
Water addedConcentrationPer 10 unitsPer 1 unit
2 mL30 mg/mL3 mg300 mcg
3 mL20 mg/mL2 mg200 mcg
5 mL12 mg/mL1.2 mg120 mcg
10 mL6 mg/mL600 mcg60 mcg

Syringe units by amount

The amounts below are examples to show the conversion, not doses. How much to take is a decision for you and your prescriber.

Units on a U-100 syringe from a 60 mg vial.
Water added1.25 mg2.5 mg5 mg
2 mL4.2 units8.3 units16.7 units
3 mL6.3 units12.5 units25 units
5 mL10.4 units20.8 units41.7 units
10 mL20.8 units41.7 units83.3 units

A 60 mg vial holds 48 draws of 1.25 mg, 24 draws of 2.5 mg, 12 draws of 5 mg, no matter how much water you add.

How far a 60 mg vial goes

Draws per vial depend only on the amount per draw, not on the water. The volume and units columns use 10 mL of water (6 mg/mL). Example amounts only, not doses.

60 mg vial: draws, volume and units per example amount.
Amount per drawDraws per vialVolume per drawUnits per draw
625 mcg960.104 mL10.4 units
1.25 mg480.208 mL20.8 units
2.5 mg240.417 mL41.7 units
5 mg120.833 mL83.3 units
10 mg61.667 mLover 1 mL

Real counts run a little lower: some liquid stays in the syringe and at the bottom of the vial.

60 mg next to other tirzepatide vial sizes

To get the same 6 mg/mL from another vial size, scale the water with the vial. Same strength means the same units for the same amount, whichever vial it comes from.

Water for 6 mg/mL, and 2.5 mg draws per vial, by vial size.
VialWater for 6 mg/mL2.5 mg draws per vial
5 mg0.83 mL2
10 mg1.67 mL4
15 mg2.5 mL6
20 mg3.33 mL8
30 mg5 mL12
40 mg6.67 mL16
50 mg8.33 mL20
60 mg (this page)10 mL24

The math

  1. Concentration. 60 mg ÷ 10 mL = 6 mg/mL
  2. Volume to draw. amount ÷ 6 mg/mL = mL
  3. Syringe units. mL × 100 = units

For a different water volume or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.

Other tirzepatide vial sizes: Tirzepatide 5 mg · Tirzepatide 10 mg · Tirzepatide 15 mg · Tirzepatide 20 mg · Tirzepatide 30 mg · Tirzepatide 40 mg · Tirzepatide 50 mg

Half-life, time to peak and sources are on the main Tirzepatide guide.

Frequently asked questions

How much bacteriostatic water do I add to a 60 mg tirzepatide vial?+
There is no single right amount. More water makes each draw bigger and easier to measure; less water keeps the volume small. With 10 mL, a 60 mg vial is 6 mg/mL, so every 10 units on a U-100 insulin syringe holds 600 mcg. With 2 mL it is 30 mg/mL (3 mg per 10 units). With 3 mL it is 20 mg/mL (2 mg per 10 units). With 5 mL it is 12 mg/mL (1.2 mg per 10 units).
How many units is 2.5 mg of tirzepatide from a 60 mg vial?+
With 10 mL of water the vial is 6 mg/mL, so 2.5 mg is 0.417 mL, or 41.7 units on a U-100 syringe. With a different water volume the units change but the amount does not. The amount is an example for the math, not a recommendation.
How many 2.5 mg draws are in a 60 mg tirzepatide vial?+
24 (60 mg ÷ 2.5 mg), whatever volume of water you add. In practice a little is lost to the syringe dead space and the last drops in the vial.