[GLP-1 · Tirzepatide · 15 mg vial]

Tirzepatide 15 mg reconstitution: how much water and how many units

Water volume chart · Syringe units · Draws per vial

Short answer: 2 mL of bacteriostatic water in a 15 mg tirzepatide vial makes 7.5 mg/mL. On a U-100 insulin syringe (1 mL = 100 units), every 10 units then holds 750 mcg. More water gives a weaker solution and a bigger draw for the same amount; the amount in the vial stays 15 mg.

Water volume chart for a 15 mg vial

15 mg tirzepatide vial, U-100 insulin syringe.
Water addedConcentrationPer 10 unitsPer 1 unit
1 mL15 mg/mL1.5 mg150 mcg
2 mL7.5 mg/mL750 mcg75 mcg
3 mL5 mg/mL500 mcg50 mcg
5 mL3 mg/mL300 mcg30 mcg

Syringe units by amount

The amounts below are examples to show the conversion, not doses. How much to take is a decision for you and your prescriber.

Units on a U-100 syringe from a 15 mg vial.
Water added1.25 mg2.5 mg5 mg
1 mL8.3 units16.7 units33.3 units
2 mL16.7 units33.3 units66.7 units
3 mL25 units50 units100 units
5 mL41.7 units83.3 unitsover 1 mL

A 15 mg vial holds 12 draws of 1.25 mg, 6 draws of 2.5 mg, 3 draws of 5 mg, no matter how much water you add.

The math

  1. Concentration. 15 mg ÷ 2 mL = 7.5 mg/mL
  2. Volume to draw. amount ÷ 7.5 mg/mL = mL
  3. Syringe units. mL × 100 = units

For a different water volume or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.

Other tirzepatide vial sizes

Tirzepatide 5 mg · Tirzepatide 10 mg · Tirzepatide 20 mg · Tirzepatide 30 mg

Half-life, time to peak and sources are on the main Tirzepatide guide.

Frequently asked questions

How much bacteriostatic water do I add to a 15 mg tirzepatide vial?+
There is no single right amount. More water makes each draw bigger and easier to measure; less water keeps the volume small. With 2 mL, a 15 mg vial is 7.5 mg/mL, so every 10 units on a U-100 insulin syringe holds 750 mcg. With 1 mL it is 15 mg/mL (1.5 mg per 10 units). With 3 mL it is 5 mg/mL (500 mcg per 10 units). With 5 mL it is 3 mg/mL (300 mcg per 10 units).
How many units is 2.5 mg of tirzepatide from a 15 mg vial?+
With 2 mL of water the vial is 7.5 mg/mL, so 2.5 mg is 0.333 mL, or 33.3 units on a U-100 syringe. With a different water volume the units change but the amount does not. The amount is an example for the math, not a recommendation.
How many 2.5 mg draws are in a 15 mg tirzepatide vial?+
6 (15 mg ÷ 2.5 mg), whatever volume of water you add. In practice a little is lost to the syringe dead space and the last drops in the vial.