Thymosin alpha-1 (thymalfasin) is a 28-amino-acid peptide first isolated from the thymus. It is approved in some countries as Zadaxin, but not in the US.
Also known as: Thymalfasin, Zadaxin, TA1.
Zadaxin comes as a 1.6 mg vial. Other powder vials are usually labeled 5 mg or 10 mg.
Here is the math for a 5 mg vial mixed with 2 mL of bacteriostatic water, drawing 1 mg with a U-100 insulin syringe (1 mL = 100 units).
5 mg ÷ 2 mL = 2.5 mg/mL1 mg ÷ 2.5 mg/mL = 0.4 mL0.4 mL × 100 = 40 units| Amount | Volume | U-100 syringe |
|---|---|---|
| 500 mcg | 0.2 mL | 20 units |
| 1 mg | 0.4 mL | 40 units |
| 2 mg | 0.8 mL | 80 units |
Adding more water doesn't change how much Thymosin Alpha-1 is in the vial. It only spreads it over more liquid, so each draw is bigger and easier to read.
| Water added | Concentration | Volume | U-100 syringe |
|---|---|---|---|
| 1 mL | 5 mg/mL | 0.2 mL | 20 units |
| 2 mL | 2.5 mg/mL | 0.4 mL | 40 units |
| 3 mL | 1.67 mg/mL | 0.6 mL | 60 units |
| 5 mL | 1 mg/mL | 1 mL | 100 units |
For any other vial size or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.
A 2001 review in the American Journal of Health-System Pharmacy reports peak serum levels within about 2 hours and a serum half-life of about 2 hours.
Numbers shown are the values Dose Track uses, listed only where they agree with the source above. Half-life varies from person to person and with injection site.