How to Store Provigil and Nuvigil (C-IV)
[Storage · Provigil and Nuvigil]

How to store Provigil and Nuvigil

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Both labels say store at 68-77°F (20-25°C), with no excursion range stated. Both are Schedule IV controlled substances, and the Medication Guides say to keep them in a safe place to prevent misuse and abuse; selling or giving them away is against the law. Neither label gives a fridge instruction or a disposal method. Sources: each label, section 16, and the Medication Guides.

What do the two labels say?

Provigil (modafinil) and Nuvigil (armodafinil) are wakefulness tablets for narcolepsy, obstructive sleep apnea and shift work disorder.

Provigil and Nuvigil US prescribing information, section 16, and Medication Guides.
ProductSection 16Medication GuidePackaging
Provigil 100 mg and 200 mg20-25°C (68-77°F); excursions not statedRoom temperature 68-77°F (20-25°C)Bottles of 30
Nuvigil 50, 150, 200 and 250 mg20-25°C (68-77°F); excursions not statedRoom temperature 68-77°F (20-25°C)Bottles of 30

Why does a safe place matter?

Both are C-IV. The Provigil Medication Guide: “Keep PROVIGIL in a safe place to prevent misuse and abuse. Selling or giving away PROVIGIL may harm others, and is against the law.” The Nuvigil guide says the same.

Neither label describes how to dispose of unused tablets; ask your pharmacist.

Dosing and comparisons

See the Provigil and Nuvigil dosing schedules, missed-dose rules for Provigil and Nuvigil, side effects for Provigil and Nuvigil, and modafinil vs armodafinil.

How do you travel with them?

No ice pack is needed. Keep tablets in the labeled pharmacy bottle in your carry-on, at room temperature and out of a hot car.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.

Frequently asked questions

Does Provigil need to be refrigerated?+
The label gives no fridge instruction. It says store at 68-77°F (20-25°C).
How should Nuvigil be stored?+
At room temperature, 68-77°F (20-25°C), in a safe place to prevent misuse and abuse, per the Medication Guide.
How do I get rid of unused modafinil?+
The Provigil and Nuvigil labels do not give a disposal method. Ask your pharmacist.