How to Store Contrave Tablets
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[Storage · Contrave]

How to store Contrave (naltrexone and bupropion)

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Store Contrave at room temperature. Section 16 says 77°F (25°C) with excursions to 59-86°F (15-30°C) permitted; the Medication Guide says 68-77°F (20-25°C). The label gives no fridge instruction. Contrave comes in bottles of 120 extended-release tablets, which are not cut, chewed or crushed. Source: Contrave label, section 16 and Medication Guide.

What does the Contrave label say?

Section 16: “Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F).” The Medication Guide: “Store CONTRAVE at room temperature between 68°F to 77°F (20°C to 25°C).”

Contrave US prescribing information, section 16, and Medication Guide.
QuestionLabel answer
Temperature77°F (25°C); Medication Guide: 68-77°F (20-25°C)
Excursions59-86°F (15-30°C) permitted
PackagingBottles of 120 extended-release tablets, 8 mg/90 mg
HandlingTablets should not be cut, chewed or crushed

Why not cut or crush Contrave?

Contrave tablets are extended-release. The dosing section says they should not be cut, chewed or crushed, and the bottle label repeats it. That is a handling rule, not a storage one, but it matters if you use a pill organizer: whole tablets only. See the Contrave dosing schedule and missed a Contrave dose.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.
Qsymia68-77°F, tightly closed and dry. FoundayoRoom-temperature tablets, 68-77°F; no fridge. Clomid, Arimidex, levothyroxineRoom temperature tablets and capsules, and which ones the labels say to keep dry or dark.

Frequently asked questions

Does Contrave need to be refrigerated?+
No fridge instruction is given. Store it at room temperature, 68-77°F (20-25°C), with excursions to 59-86°F (15-30°C) permitted.
Can I split Contrave tablets?+
No. The label says the tablets should not be cut, chewed or crushed.
How many tablets come in a Contrave bottle?+
120 extended-release tablets of 8 mg naltrexone and 90 mg bupropion each (section 16).

Sources

  1. Contrave (naltrexone HCl and bupropion HCl) extended-release tablets US prescribing information, DailyMed

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