Short answer: All four labels say store at 68-77°F (20-25°C). Januvia, Janumet and Tradjenta allow excursions to 59-86°F (15-30°C); the generic metformin label used here states no excursion range and says to dispense it in light-resistant containers. None gives a fridge instruction. Sources: each label, section 16, and the patient leaflets.
Metformin is the usual first tablet for type 2 diabetes. Januvia (sitagliptin) and Tradjenta (linagliptin) are DPP-4 inhibitors, and Janumet combines sitagliptin with metformin. Metformin is sold by many makers; this page uses the current Zydus metformin tablet label, and others carry their own.
| Product | Section 16 | Patient leaflet | Other |
|---|---|---|---|
| Metformin hydrochloride tablets (Zydus) | 20-25°C (68-77°F); excursions not stated | 20-25°C (68-77°F) | Dispense in light-resistant containers |
| Januvia | 20-25°C (68-77°F); excursions 15-30°C (59-86°F) | Room temperature 68-77°F (20-25°C) | Includes unit-of-use blister calendar packages of 30 |
| Janumet | 20-25°C (68-77°F); excursions 15-30°C (59-86°F) | Room temperature 68-77°F (20-25°C) | Unit-of-use bottles of 60 or 180 |
| Tradjenta | 20-25°C (68-77°F); excursions 15-30°C (59-86°F) | Room temperature 68-77°F (20-25°C) | If repackaged, dispense in a tight container |
Metformin section 16.2: “Store at 20°C to 25°C (68°F to 77°F) [See USP Controlled Room Temperature]. Dispense in light-resistant containers.” Keeping it in the pharmacy bottle covers both.
Dosing: metformin, Januvia, Janumet and Tradjenta. Missed a dose: metformin, Januvia, Janumet, Tradjenta. Comparisons: Januvia vs Janumet, Januvia vs Tradjenta and metformin vs Jardiance.
No ice pack is needed. Keep tablets in the labeled bottle or blister pack in your carry-on, within the label range, and out of a hot car. For metformin, the label gives 68-77°F (20-25°C) without an excursion range, so avoid long spells outside it.