Short answer: The Tradjenta label says to take a missed dose as soon as you remember and not to double the next dose. The Medication Guide adds that if you do not remember until it is time for your next dose, skip the missed one and go back to your regular schedule. Tradjenta is 5 mg once a day.
| Situation | What the label says |
|---|---|
| Schedule | 5 mg once daily, with or without food (2.1) |
| Missed a dose | Take it as soon as you remember (17) |
| Time for the next dose | Skip the missed dose; back to the regular schedule (Medication Guide) |
| Doubling up | Do not double the next dose (17) |
| Half-life | Long terminal half-life, more than 100 hours (12.3) |
Section 17 says that if a dose is missed, it should be taken as soon as the patient remembers, and not to double the next dose.
The Medication Guide says: if you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Tradjenta at the same time.
Section 12.3 says linagliptin levels fall in at least two phases, with a long terminal half-life of more than 100 hours, related to its saturable binding to DPP-4. The label adds that this long final phase does not cause the drug to build up.
The label does not discuss late doses. The Medication Guide says low blood sugar can happen more often when Tradjenta is taken with certain other diabetes medicines.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.