Short answer: The Januvia Patient Information says to take a missed dose as soon as you remember. If you do not remember until it is time for your next dose, skip the missed one and go back to your regular schedule. Do not take two doses of Januvia at the same time. Januvia is 100 mg once a day for most adults.
| Situation | What the label says |
|---|---|
| Schedule | 100 mg once daily, with or without food (2.1) |
| Missed a dose | Take it as soon as you remember (Patient Information) |
| Time for the next dose | Skip the missed dose; go back to the regular schedule (Patient Information) |
| Doubling up | Do not take two doses at the same time (Patient Information) |
| Half-life | About 12.4 hours (12.3) |
The prescribing information itself has no missed-dose section. The Patient Information, which is part of the same FDA label, says: if you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Januvia at the same time.
Example: you take Januvia with breakfast and remember at 3 p.m. Under the label you would take it then. If you only remember the next morning, you would skip it and take one tablet as usual.
Yes. Section 2.1 gives 100 mg once daily. Section 2.2 lowers it to 50 mg once daily when eGFR is 30 to under 45 mL/min/1.73 m2, and to 25 mg once daily when eGFR is under 30 or on dialysis. A missed dose is handled the same way at any of these doses.
Section 12.3 gives an apparent terminal half-life of 12.4 hours after a single 100 mg dose in healthy volunteers.
The label does not discuss late doses. Section 5.4 says low blood sugar was more common when Januvia was used with insulin or a sulfonylurea, and that a lower dose of those medicines may be needed. Taking two Januvia doses at once is what the Patient Information rules out.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.