Missed a Soliqua Dose? What the FDA Label Says
[Missed dose · Soliqua]

I missed my Soliqua dose. What should I do?

insulin glargine and lixisenatide · Once daily, within 1 hour before the first meal · Label checked

Short answer: The Soliqua 100/33 label says to resume your once-daily schedule with the next scheduled dose. Do not take an extra dose or increase the dose to make up for the missed one. Soliqua is taken within the hour before the first meal of the day, so a missed morning dose waits until the next morning.

What does the Soliqua label say about missed doses?

From the FDA label on DailyMed. Numbers in brackets are label section numbers.
SituationWhat the label says
ScheduleOnce daily, within 1 hour before the first meal (2.1)
Missed a doseResume with the next scheduled dose (2.4)
Extra doseDo not take an extra dose or increase the dose (2.4)
Most per day60 units (2.1)
Several days missedNo specific rule in the label

What does the label say about a missed Soliqua dose?

Section 2.4 says patients who miss a dose should resume the once-daily schedule with the next scheduled dose, and should not take an extra dose or increase the dose to make up for it. The Medication Guide puts it as: take your next scheduled dose at your regular time.

Example: you usually inject before breakfast at 7 a.m. and realize at lunch that you forgot. Under the label you would not inject at lunch; you would take your usual dose before breakfast the next morning.

Why is the dose tied to the first meal?

Section 2.1 says Soliqua is injected once a day within the hour before the first meal of the day. It contains lixisenatide, a GLP-1 with a short half-life of about 3 hours (section 12.3), which works mainly on the meal that follows the dose.

What if I missed several days of Soliqua?

The Soliqua label does not say what to do after several missed days. That is a question for your prescriber.

Soliqua is dosed from 15 to 60 units (section 2.1). Do not change the number of units on your own after a gap.

This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.

Missed-dose rules for other medicines

Frequently asked questions

Can I take Soliqua with lunch if I missed breakfast?+
The label says to take your next scheduled dose at your regular time and not to take an extra dose. Ask your prescriber if your meal pattern changes.
Can I double Soliqua to catch up?+
No. Section 2.4 says not to take an extra dose or increase the dose.
What is the most Soliqua I can take in a day?+
60 units, according to section 2.1.