Short answer: The Gonal-f RFF Redi-ject label says that if a dose is missed or forgotten, the next dose should not be doubled, and you should call your healthcare provider for further dosing instructions. The Gonal-f multi-dose kit label says the same. Each dose is set by your clinic, so there is no general catch-up rule.
| Situation | What the label says |
|---|---|
| Schedule | Daily under the skin (2.2, 2.3) |
| Missed a dose | Call your healthcare provider for dosing instructions (17.3) |
| Doubling up | Do not double the next dose (17.3) |
| ART starting dose | 150 International Units a day; 225 if 35 or older with suppressed levels (2.3) |
| Pen after first use | Up to 28 days, then discard (16.2) |
Section 17.3 of the Gonal-f RFF Redi-ject prescribing information tells prescribers to inform women that if a dose is missed or forgotten, the next dose should not be doubled and she should call her healthcare provider for further dosing instructions.
The separate Gonal-f multi-dose kit label has the same rule in section 2.6: do not double the next dose if a dose is missed or forgotten.
Section 2.3 says the dose for assisted reproduction is individualized: it usually starts at 150 International Units a day from cycle day 2 or 3, is adjusted after 5 days based on ultrasound and blood estradiol levels, and is not changed more often than every 3 to 5 days. Doses above 450 International Units a day are not recommended. A missed day changes that picture, so the clinic sets the next step.
No. Section 16.2 says that after the first injection the pen is kept in the fridge or at 68-77°F (20-25°C) for up to 28 days, and unused medicine is discarded after 28 days.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.