Forgot to Change Your Estradiol Patch? FDA Label Rule
[Missed dose · Estradiol patch (Vivelle-Dot, Climara)]

I forgot to change my estradiol patch. What should I do?

estradiol transdermal system · Vivelle-Dot changed twice weekly; Climara changed once weekly · Label checked

Short answer: The Vivelle-Dot and Climara labels both say that if you forget to apply a new patch, put on a new one as soon as possible. Vivelle-Dot says to keep the original change schedule after that. Both labels note that missing patches can bring spotting, bleeding or a return of symptoms.

What does the Estradiol patch (Vivelle-Dot, Climara) label say about missed doses?

From the FDA label on DailyMed. Numbers in brackets are label section numbers.
SituationWhat the label says
Vivelle-Dot scheduleNew patch twice weekly (Vivelle-Dot 2.5)
Climara scheduleNew patch once weekly (Climara 2.1)
Forgot to change itApply a new patch as soon as possible (Vivelle-Dot 2.5; Climara Patient Information)
After a late changeKeep the original schedule (Vivelle-Dot 2.5)
Patch fell offVivelle-Dot: reapply it or a new one; Climara: reapply elsewhere or new one for rest of the week

What does the Vivelle-Dot label say?

Section 2.5 says that if a woman has forgotten to apply Vivelle-Dot, she should apply a new patch as soon as possible and then follow the original treatment schedule. It adds that interrupting treatment may make breakthrough bleeding, spotting and a return of symptoms more likely.

Example: you change Vivelle-Dot on Sundays and Thursdays and remember on Friday that you skipped Thursday. Under the label you would put on a new patch Friday and still change it on Sunday.

What does the Climara label say?

Climara is changed once a week. The Patient Information says that if you forget to apply a new Climara patch, apply a new one as soon as possible. It also warns that stopping or forgetting patches can cause spotting or bleeding and symptoms may come back.

If a Climara patch falls off, section 2.5 says to reapply it to a different spot, or if it will not stick, apply a new one for the rest of the 7-day interval. Wear only one patch at a time.

What if my Vivelle-Dot patch fell off?

Section 2.5 says to reapply the same patch or apply a new one to another spot, and in either case keep the original schedule.

This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.

Missed-dose rules for other medicines

Frequently asked questions

I forgot to change my estrogen patch. Do I wear two?+
No. Take off the old one and apply a new patch as soon as possible. Climara's label says to wear only one at a time.
Do I start a new schedule after a late patch change?+
Vivelle-Dot's label says to keep the original treatment schedule.
Why did I spot after forgetting a patch?+
Both labels say missed or stopped patches can cause spotting or bleeding and symptoms coming back.