Subcutaneous Injection (SubQ): What It Means
[Glossary · Injecting]

Subcutaneous injection (SubQ)

Also called SubQ, sub-Q, SC injection, under the skin injection · Reviewed

Definition: A subcutaneous injection (SubQ) puts medicine into the layer of fat just under the skin, above the muscle. GLP-1 pens like Wegovy and Mounjaro are labeled for subcutaneous use, and so is one testosterone product, Xyosted. Most peptides people track are also given this way.

Where labels say to inject

The Wegovy label says to inject in the abdomen, thigh, or upper arm. The Mounjaro label lists the abdomen or thigh, or the back of the upper arm if another person gives the shot. Both labels say to rotate injection sites with each dose.

Xyosted, a testosterone enanthate autoinjector, is labeled for subcutaneous injection in the abdominal region only, and its label says to avoid intramuscular or intravascular injection. That is a useful reminder that the route belongs to the product: the same hormone can be labeled SubQ in one product and intramuscular in another.

Why it matters when you track doses

The route changes how a drug is absorbed, so a dose given SubQ and the same dose given into muscle are not the same event. Log the route along with the site. If you switch routes, note the date so you can read later changes in how you feel against it.

Site matters too. Repeated SubQ shots into one patch of skin can cause lumps of thickened fat (lipohypertrophy) that absorb medicine unevenly. Dose Track lets you log the injection site with each dose, which makes a rotation easy to see at a glance.

Common mix-ups

  • SubQ vs IM. SubQ goes into fat; intramuscular (IM) goes into muscle. A label that names one route does not cover the other.
  • "Subcutaneous" vs "intradermal". Intradermal means into the skin itself, which is shallower. It is a different route.
  • Same site every time. Labels for both Wegovy and Mounjaro say to rotate with each dose, not just now and then.

Read more on Dose Track: Why injection site rotation matters · Wegovy guide · Mounjaro guide

General education drawn from labels and published studies, not personal medical advice. Your prescriber, pharmacist and the label that came with your product are the final word.

Frequently asked questions

Is SubQ the same as intramuscular?+
No. A subcutaneous injection goes into the fat under the skin, and an intramuscular injection goes deeper, into muscle. Each product label names its route.
Where do GLP-1 labels say to inject?+
The Wegovy label lists the abdomen, thigh, or upper arm. The Mounjaro label lists the abdomen or thigh, or the back of the upper arm if someone else gives the shot.
Can testosterone be given subcutaneously?+
One US product, Xyosted, is labeled for subcutaneous injection in the abdomen only. Depo-Testosterone is labeled for intramuscular use only. The route belongs to the product, so check the label for the one you use.