Peptide Blend: What It Means and How to Log It
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Blend (peptide blend)

Also called peptide blend, combo vial, pre-mixed blend · Reviewed

Definition: A blend is a single vial that holds two or more peptides mixed together, such as BPC-157 with TB-500, or CJC-1295 with ipamorelin. One draw from the vial gives a fixed ratio of each. "Blend" is a community and seller word, not a medical or regulatory term.

Worked example

Every shot from a blend is really one dose of each peptide in it. Here is the math, for arithmetic only.

Splitting one draw into its parts

  1. A vial holds 10 mg BPC-157 and 10 mg TB-500. It is mixed with 2 mL of BAC water.
  2. Each peptide is now 10 mg ÷ 2 mL = 5 mg/mL.
  3. A draw of 10 units on a U-100 syringe is 0.1 mL. 0.1 mL × 5 mg/mL = 0.5 mg, which is 500 mcg of each.
  4. You cannot change one without changing the other. A bigger draw raises both.

What evidence exists

Very little. FDA reviewed several of the peptides sold in blends for use in compounding. For BPC-157 it found no or only limited safety information for the proposed routes. For the TB-500 fragment it found no human exposure data. For CJC-1295 it noted serious adverse events including increased heart rate. We found no human trials of these peptides given together as a blend.

A blend also stacks the uncertainties: if something goes wrong, there is no way to tell which ingredient caused it.

Why it matters when you track doses

Log a blend as one shot that delivered each component, so your totals per compound stay right when you also take one of them on its own. Keep the ratio with the vial; a different vial may use a different ratio.

Read more on Dose Track: Peptide blends · Peptide blend calculator · BPC-157 + TB-500 blend · CJC-1295 + ipamorelin blend

General education drawn from labels and published studies, not personal medical advice. Your prescriber, pharmacist and the label that came with your product are the final word.
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Frequently asked questions

What is the difference between a blend and a stack?+
A blend is two or more peptides in one vial, so one shot gives all of them. A stack is several compounds taken in the same period, usually as separate shots or pills.
Are peptide blends FDA approved?+
No. FDA has found no or limited human safety data for several common blend ingredients, such as BPC-157 and the TB-500 fragment.
How do I work out the dose of each peptide in a blend?+
Divide each peptide's milligrams by the liquid added to get its strength, then multiply by the volume you draw. 10 mg in 2 mL is 5 mg/mL, so 0.1 mL holds 0.5 mg.

Sources

  1. FDA: Certain bulk drug substances for use in compounding that may present significant safety risks

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