Short answer: The Foundayo label says a missed dose is taken as soon as possible, without doubling the next dose, and the Medication Guide adds not to take 2 doses in one day. After 7 or more missed doses in a row, the step-up restarts at a lower dose. With a strong CYP3A4 inhibitor, the maximum is 9 mg once daily. Each step up comes after at least 30 days.
Full dosing chart: Foundayo dosing chart, every dose, step by step
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Foundayo is approved for: Foundayo is approved, with a reduced-calorie diet and more physical activity, to reduce excess body weight and keep it off long term in adults with obesity, or adults with overweight and at least one weight-related condition (section 1). The label says using it with another GLP-1 receptor agonist is not recommended.
Source
FOUNDAYO (orforglipron) tablets, for oral use, prescribing information and Medication Guide. Eli Lilly. DailyMed, version published August 13, 2026. DailyMed setid 8ac446c5-feba-474f-a103-23facb9b5c62
If a dose is missed, it is taken as soon as possible, without doubling up the next dose. The Medication Guide adds not to take 2 doses in the same day. If 7 or more doses in a row are missed, the step-up is restarted at a lower dose to reduce the risk of stomach and gut side effects.
More on this: missed a dose of Foundayo.
The label says to follow the starting dose and step-up schedule to reduce the risk of stomach and gut side effects.
With a strong CYP3A4 inhibitor, the maximum Foundayo dose is 9 mg once daily. Strong CYP3A4 inhibitors that also block OATP1B (for example ritonavir) are avoided.
Strong CYP3A4 inducers are avoided. With moderate CYP3A4 inducers, Foundayo's effect is monitored and the dose raised as needed.
Simvastatin is kept at no more than 20 mg once daily with Foundayo, because Foundayo doubled exposure to simvastatin's active form.
When starting Foundayo, a lower dose of insulin or a sulfonylurea may be considered to reduce the risk of low blood sugar.
No dose change is recommended for mild or moderate liver impairment; Foundayo is not recommended in severe liver impairment (Child-Pugh C). No dose change is recommended for kidney impairment (section 8.7).
The label says using Foundayo with another GLP-1 receptor agonist is not recommended. It gives no instructions for switching from another GLP-1 medicine.
Foundayo is a tablet taken by mouth once a day, with or without food. Tablets are swallowed whole, not broken, crushed or chewed, and no more than one tablet is taken per day (section 2.1).
It comes in six strengths: 0.8 mg, 2.5 mg, 5.5 mg, 9 mg, 14.5 mg and 17.2 mg (section 3). It is used with a reduced-calorie diet and more physical activity (section 1).
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets. The Foundayo dosing chart lays it out step by step, with the weeks or days each dose covers.
| Step | Once-daily dose | What the label says |
|---|---|---|
| Start | 0.8 mg | Starting dose; at least 30 days |
| Step 2 | 2.5 mg | After at least 30 days on 0.8 mg; at least 30 days |
| Step 3 | 5.5 mg | After at least 30 days on 2.5 mg |
| Optional step | 9 mg | After at least 30 days on the current dose, based on treatment response and tolerability |
| Optional step | 14.5 mg | After at least 30 days on the current dose, based on treatment response and tolerability |
| Optional step | 17.2 mg | Maximum dose |
In Dose Track you set up Foundayo as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.