Short answer: 2 mL of bacteriostatic water in a 10 mg survodutide vial makes 5 mg/mL. On a U-100 insulin syringe (1 mL = 100 units), every 10 units then holds 500 mcg. More water gives a weaker solution and a bigger draw for the same amount; the amount in the vial stays 10 mg.
| Water added | Concentration | Per 10 units | Per 1 unit |
|---|---|---|---|
| 1 mL | 10 mg/mL | 1 mg | 100 mcg |
| 2 mL | 5 mg/mL | 500 mcg | 50 mcg |
| 3 mL | 3.33 mg/mL | 333.333 mcg | 33.333 mcg |
| 5 mL | 2 mg/mL | 200 mcg | 20 mcg |
The amounts below are examples to show the conversion, not doses. How much to take is a decision for you and your prescriber.
| Water added | 1.2 mg | 2.4 mg | 4.8 mg |
|---|---|---|---|
| 1 mL | 12 units | 24 units | 48 units |
| 2 mL | 24 units | 48 units | 96 units |
| 3 mL | 36 units | 72 units | over 1 mL |
| 5 mL | 60 units | over 1 mL | over 1 mL |
A 10 mg vial holds 8.3 draws of 1.2 mg, 4.2 draws of 2.4 mg, 2.1 draws of 4.8 mg, no matter how much water you add.
Draws per vial depend only on the amount per draw, not on the water. The volume and units columns use 2 mL of water (5 mg/mL). Example amounts only, not doses.
| Amount per draw | Draws per vial | Volume per draw | Units per draw |
|---|---|---|---|
| 600 mcg | 16.7 | 0.12 mL | 12 units |
| 1.2 mg | 8.3 | 0.24 mL | 24 units |
| 2.4 mg | 4.2 | 0.48 mL | 48 units |
| 4.8 mg | 2.1 | 0.96 mL | 96 units |
| 9.6 mg | 1 | 1.92 mL | over 1 mL |
Real counts run a little lower: some liquid stays in the syringe and at the bottom of the vial.
10 mg ÷ 2 mL = 5 mg/mLamount ÷ 5 mg/mL = mLmL × 100 = unitsFor a different water volume or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.
Half-life, time to peak and sources are on the main Survodutide guide.