Retatrutide 40 mg Reconstitution: BAC Water & Units
[GLP-1 · Retatrutide · 40 mg vial]

Retatrutide 40 mg reconstitution: how much water and how many units

Water volume chart · Syringe units · Draws per vial

Short answer: 10 mL of bacteriostatic water in a 40 mg retatrutide vial makes 4 mg/mL. On a U-100 insulin syringe (1 mL = 100 units), every 10 units then holds 400 mcg. More water gives a weaker solution and a bigger draw for the same amount; the amount in the vial stays 40 mg.

Water volume chart for a 40 mg vial

40 mg retatrutide vial, U-100 insulin syringe.
Water addedConcentrationPer 10 unitsPer 1 unit
2 mL20 mg/mL2 mg200 mcg
3 mL13.33 mg/mL1.333 mg133.333 mcg
5 mL8 mg/mL800 mcg80 mcg
10 mL4 mg/mL400 mcg40 mcg

Syringe units by amount

The amounts below are examples to show the conversion, not doses. How much to take is a decision for you and your prescriber.

Units on a U-100 syringe from a 40 mg vial.
Water added1 mg2 mg4 mg
2 mL5 units10 units20 units
3 mL7.5 units15 units30 units
5 mL12.5 units25 units50 units
10 mL25 units50 units100 units

A 40 mg vial holds 40 draws of 1 mg, 20 draws of 2 mg, 10 draws of 4 mg, no matter how much water you add.

How far a 40 mg vial goes

Draws per vial depend only on the amount per draw, not on the water. The volume and units columns use 10 mL of water (4 mg/mL). Example amounts only, not doses.

40 mg vial: draws, volume and units per example amount.
Amount per drawDraws per vialVolume per drawUnits per draw
500 mcg800.125 mL12.5 units
1 mg400.25 mL25 units
2 mg200.5 mL50 units
4 mg101 mL100 units
8 mg52 mLover 1 mL

Real counts run a little lower: some liquid stays in the syringe and at the bottom of the vial.

40 mg next to other retatrutide vial sizes

To get the same 4 mg/mL from another vial size, scale the water with the vial. Same strength means the same units for the same amount, whichever vial it comes from.

Water for 4 mg/mL, and 2 mg draws per vial, by vial size.
VialWater for 4 mg/mL2 mg draws per vial
5 mg1.25 mL2.5
10 mg2.5 mL5
15 mg3.75 mL7.5
20 mg5 mL10
30 mg7.5 mL15
40 mg (this page)10 mL20
50 mg12.5 mL (over 10 mL)25
60 mg15 mL (over 10 mL)30

The math

  1. Concentration. 40 mg ÷ 10 mL = 4 mg/mL
  2. Volume to draw. amount ÷ 4 mg/mL = mL
  3. Syringe units. mL × 100 = units

For a different water volume or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.

Other retatrutide vial sizes: Retatrutide 5 mg · Retatrutide 10 mg · Retatrutide 15 mg · Retatrutide 20 mg · Retatrutide 30 mg · Retatrutide 50 mg · Retatrutide 60 mg

Half-life, time to peak and sources are on the main Retatrutide guide.

Frequently asked questions

How much bacteriostatic water do I add to a 40 mg retatrutide vial?+
There is no single right amount. More water makes each draw bigger and easier to measure; less water keeps the volume small. With 10 mL, a 40 mg vial is 4 mg/mL, so every 10 units on a U-100 insulin syringe holds 400 mcg. With 2 mL it is 20 mg/mL (2 mg per 10 units). With 3 mL it is 13.33 mg/mL (1.333 mg per 10 units). With 5 mL it is 8 mg/mL (800 mcg per 10 units).
How many units is 2 mg of retatrutide from a 40 mg vial?+
With 10 mL of water the vial is 4 mg/mL, so 2 mg is 0.5 mL, or 50 units on a U-100 syringe. With a different water volume the units change but the amount does not. The amount is an example for the math, not a recommendation.
How many 2 mg draws are in a 40 mg retatrutide vial?+
20 (40 mg ÷ 2 mg), whatever volume of water you add. In practice a little is lost to the syringe dead space and the last drops in the vial.