[GLP-1 · Retatrutide · 20 mg vial]

Retatrutide 20 mg reconstitution: how much water and how many units

Water volume chart · Syringe units · Draws per vial

Short answer: 2 mL of bacteriostatic water in a 20 mg retatrutide vial makes 10 mg/mL. On a U-100 insulin syringe (1 mL = 100 units), every 10 units then holds 1 mg. More water gives a weaker solution and a bigger draw for the same amount; the amount in the vial stays 20 mg.

Water volume chart for a 20 mg vial

20 mg retatrutide vial, U-100 insulin syringe.
Water addedConcentrationPer 10 unitsPer 1 unit
1 mL20 mg/mL2 mg200 mcg
2 mL10 mg/mL1 mg100 mcg
3 mL6.67 mg/mL666.667 mcg66.667 mcg
5 mL4 mg/mL400 mcg40 mcg

Syringe units by amount

The amounts below are examples to show the conversion, not doses. How much to take is a decision for you and your prescriber.

Units on a U-100 syringe from a 20 mg vial.
Water added1 mg2 mg4 mg
1 mL5 units10 units20 units
2 mL10 units20 units40 units
3 mL15 units30 units60 units
5 mL25 units50 units100 units

A 20 mg vial holds 20 draws of 1 mg, 10 draws of 2 mg, 5 draws of 4 mg, no matter how much water you add.

The math

  1. Concentration. 20 mg ÷ 2 mL = 10 mg/mL
  2. Volume to draw. amount ÷ 10 mg/mL = mL
  3. Syringe units. mL × 100 = units

For a different water volume or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.

Other retatrutide vial sizes

Retatrutide 5 mg · Retatrutide 10 mg · Retatrutide 15 mg · Retatrutide 30 mg · Retatrutide 60 mg

Half-life, time to peak and sources are on the main Retatrutide guide.

Frequently asked questions

How much bacteriostatic water do I add to a 20 mg retatrutide vial?+
There is no single right amount. More water makes each draw bigger and easier to measure; less water keeps the volume small. With 2 mL, a 20 mg vial is 10 mg/mL, so every 10 units on a U-100 insulin syringe holds 1 mg. With 1 mL it is 20 mg/mL (2 mg per 10 units). With 3 mL it is 6.67 mg/mL (666.667 mcg per 10 units). With 5 mL it is 4 mg/mL (400 mcg per 10 units).
How many units is 2 mg of retatrutide from a 20 mg vial?+
With 2 mL of water the vial is 10 mg/mL, so 2 mg is 0.2 mL, or 20 units on a U-100 syringe. With a different water volume the units change but the amount does not. The amount is an example for the math, not a recommendation.
How many 2 mg draws are in a 20 mg retatrutide vial?+
10 (20 mg ÷ 2 mg), whatever volume of water you add. In practice a little is lost to the syringe dead space and the last drops in the vial.