Gonadorelin Reconstitution Calculator, Units & Half-Life
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[TRT · Compound guide]

Gonadorelin: reconstitution, units and half-life

Vial sizes · Worked example · Units chart · Half-life notes

What is gonadorelin?

Gonadorelin is a synthetic copy of gonadotropin-releasing hormone (GnRH), the brain hormone that tells the pituitary to release LH and FSH. Every gonadorelin product we found on DailyMed is a veterinary injection (Factrel, for example, is labeled for cattle); none is labeled for people.

Also known as: GnRH, LHRH.

Common vial sizes

Veterinary gonadorelin (for example Factrel) is a ready-made solution. Powder vials are usually labeled 2 mg or 10 mg.

Water and syringe-unit charts by vial size: 2 mg · 10 mg

Worked reconstitution example

Here is the math for a 2 mg vial mixed with 2 mL of bacteriostatic water, drawing 100 mcg with a U-100 insulin syringe (1 mL = 100 units).

  1. Concentration. 2 mg ÷ 2 mL = 1 mg/mL
  2. Volume to draw. 100 mcg ÷ 1 mg/mL = 0.1 mL
  3. Syringe units. 0.1 mL × 100 = 10 units
The amount here is an example to show the math, not a recommendation. How much to take is a decision for you and your prescriber.

Units chart at 1 mg/mL

2 mg vial + 2 mL water. Amounts are examples for the conversion, not doses.
AmountVolumeU-100 syringe
50 mcg0.05 mL5 units
100 mcg0.1 mL10 units
200 mcg0.2 mL20 units

Same amount, different water volumes

Adding more water doesn't change how much gonadorelin is in the vial. It only spreads it over more liquid, so each draw is bigger and easier to read.

100 mcg from a 2 mg vial.
Water addedConcentrationVolumeU-100 syringe
1 mL2 mg/mL0.05 mL5 units
2 mL1 mg/mL0.1 mL10 units
3 mL666.7 mcg/mL0.15 mL15 units
5 mL400 mcg/mL0.25 mL25 units

For any other vial size or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.

What do human studies show?

The human studies are older and used GnRH to treat men whose brain does not make enough of it (hypogonadotropic hypogonadism). In a 1982 NEJM study, six men given small, regular pulses under the skin by a portable pump reached normal adult LH and FSH within a week, and testosterone rose from 77 to 520 ng/dL after one month.

A 1987 study in 30 men compared 500 mcg injected twice daily with a pump giving a pulse every 90 minutes; the pump gave better hormone responses and sperm counts. GnRH works in pulses, which is why those studies used pumps. Its use to keep the testes active on TRT has not been tested in a published trial we could find.

These are trial protocols, not personalized advice; confirm any dosing with your prescriber.

Gonadorelin half-life and time to peak

  • Half-lifeNot listed
  • Time to peak (Tmax)Not listed

We could not open a primary human source that gives a half-life for gonadorelin injected under the skin, so we do not list one here.

How to track gonadorelin in Dose Track

  1. Add gonadorelin as a custom compound. It is not in the built-in list, but a custom compound gets the same vial, units and reminder tools, and it sits next to everything else you take.
  2. Save your vial: enter the vial size and how much water you added. From then on every amount you log shows as syringe units, and the reconstitution planner suggests a water volume that lands on a clean mark.
  3. Log each shot. The app subtracts it from the vial, shows what is left, and warns you before you run out.
  4. Set reminders on your own schedule, whether that is daily, weekly or every few days.
  5. Your log stays on your phone.
hCG (Human Chorionic Gonadotropin)Novarel, Pregnyl · half-life about 29 hours Kisspeptin-10Metastin 45-54 Enclomiphene CitrateAndroxal (proposed name), trans-clomiphene Testosterone CypionateDepo-Testosterone, Test C · half-life about 8 days

Frequently asked questions

How much bacteriostatic water do I add to a 2 mg gonadorelin vial?+
There is no single right amount. More water makes each draw bigger and easier to measure; less water makes it smaller. For example, 2 mL in a 2 mg vial gives 1 mg/mL, so 100 mcg is 0.1 mL, or 10 units on a U-100 insulin syringe. That amount is only an example for the math, not a recommendation. The free Dose Track reconstitution calculator works it out for any vial and amount.
How many units is 100 mcg of gonadorelin?+
It depends on the concentration in your vial. At 1 mg/mL (2 mg mixed with 2 mL), 100 mcg is 0.1 mL, which is 10 units on a U-100 insulin syringe, where 1 mL is 100 units. Divide the amount by the concentration to get mL, then multiply by 100.
What is the half-life of gonadorelin?+
We could not open a primary human source that gives a half-life for gonadorelin injected under the skin, so we do not list one here.
Can I track gonadorelin in Dose Track?+
Yes, as a custom compound. Gonadorelin is not in the built-in list, but you can add it yourself. You can then log each shot next to your other compounds, save your vial and how much water you added so every amount shows in syringe units, see how much is left in the vial, and get reminders. Your log stays on your phone.

Sources

  1. Hoffman AR, Crowley WF Jr. Induction of puberty in men by long-term pulsatile administration of low-dose gonadotropin-releasing hormone. N Engl J Med. 1982.
  2. Shargil AA. Treatment of idiopathic hypogonadotropic hypogonadism in men with LH-RH: daily injections vs pulsatile infusion pump. Fertil Steril. 1987.
  3. Factrel (gonadorelin hydrochloride) injection label, veterinary (cattle). DailyMed, September 2026.

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