How to Store Toujeo Pens: Fridge, Then 56 Days
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[Storage · Toujeo]

How to store Toujeo (insulin glargine U-300)

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Keep new Toujeo SoloStar and Max SoloStar pens in the fridge at 36-46°F (2-8°C) until the expiration date. After first use, keep the pen at room temperature up to 86°F (30°C), cap on, for up to 56 days; do not put it back in the fridge. Throw away a pen that froze. Source: Toujeo label, section 16.2, and Instructions for Use.

What does the Toujeo label say?

Section 16.2: “TOUJEO SoloStar or TOUJEO Max SoloStar prefilled pen should not be stored in the freezer and should not be allowed to freeze. Discard TOUJEO prefilled pen if it has been frozen. Protect TOUJEO SoloStar/TOUJEO Max SoloStar from direct heat and light.”

Toujeo US prescribing information, section 16.2 storage table.
PenNot in use (unopened), refrigerated 36-46°F (2-8°C)In use (opened), room temperature only, up to 86°F (30°C)
1.5 mL SoloStar (450 units)Until expiration date56 days
3 mL Max SoloStar (900 units)Until expiration date56 days

The table says to always store the pens with the cap on during the in-use period, “to prevent degradation.” Unlike the Lantus label, the Toujeo table has no room-temperature column for unopened pens: how long an unused pen can be out of the fridge is not stated.

How do you handle the pen in use?

  • Instructions for Use: “Take a new pen out of the refrigerator at least 1 hour before you inject. Cold insulin is more painful to inject.”
  • After first use, keep the pen at room temperature up to 86°F (30°C), away from direct heat and light. Do not put it back in the refrigerator.
  • “Only use your pen for up to 56 days after its first use.” The carton says the same: use within 56 days after opening.
  • Do not store the pen with the needle attached. Store it with the pen cap on.

See Toujeo side effects, the Toujeo dosing schedule and the insulin pen glossary entry.

How do you travel with it?

An in-use Toujeo pen travels at room temperature, up to 86°F (30°C), for the rest of its 56 days. Unused spares should stay cold: the label gives them no room-temperature allowance. Keep them off direct contact with an ice pack, since a frozen pen is thrown away.

  • TSA allows medically necessary liquids over 3.4 oz in carry-on bags; declare them at the checkpoint for inspection.
  • Unused syringes and pen needles are allowed when they travel with the injectable medicine.
  • Ice packs and gel packs that keep medicine cool may go through frozen, partly frozen or melted.
  • Keep medicine in your carry-on, not checked luggage, where you cannot control the temperature. Do not let it touch an ice pack directly, since most labels say do not freeze.

More in the travel guide.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.
LantusUnopened in the fridge; 28 days once opened; in-use SoloStar pens at room temperature only. TresibaFridge until expiry, or 56 days up to 86°F; in-use pens and vials 56 days. Left out of the fridgeExact room-temperature hours and days from each label, and the temperature ceiling. Traveling with injectablesTSA rules for liquids, syringes and ice packs, plus the label temperature limits to plan around.

Frequently asked questions

How long is Toujeo good once opened?+
56 days at room temperature up to 86°F (30°C), for both the 1.5 mL SoloStar and the 3 mL Max SoloStar pen.
Should I refrigerate my Toujeo pen after I start using it?+
No. The label says in-use pens are kept at room temperature only. Do not put the pen back in the refrigerator.
How long can an unopened Toujeo pen be out of the fridge?+
The Toujeo label does not say. Its storage table lists unopened pens as refrigerated until the expiration date and gives no room-temperature time for them.
Can I use Toujeo that froze?+
No. The label says discard a Toujeo pen if it has been frozen.

Sources

  1. Toujeo (insulin glargine injection 300 units/mL) US prescribing information, DailyMed
  2. TSA: Liquid medications
  3. TSA: Unused syringes
  4. TSA: Gel ice packs

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