How to Store Evenity: Fridge, 30 Days at Up to 77°F
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[Storage · Evenity]

How to store Evenity (romosozumab-aqqg)

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Keep Evenity in the fridge at 36-46°F (2-8°C) in its carton, away from light. Do not freeze or shake it. If taken out of the fridge, it can stay at room temperature up to 77°F (25°C) in the carton but must be used within 30 days, or thrown away. Evenity is given by a healthcare provider. Source: Evenity label, section 16.2.

What does the Evenity label say?

Section 16.2: “Refrigerate EVENITY at 2°C to 8°C (36°F to 46°F) in the original carton to protect from light. Do not freeze. Do not shake.” If removed from the refrigerator, it “can be kept at room temperature up to 25°C (77°F) in the original carton and must be used within 30 days. If not used within 30 days, discard EVENITY.” Also: do not expose it to temperatures above 77°F (25°C).

Evenity US prescribing information, sections 2.3 and 16.2, and Medication Guide.
QuestionLabel answer
TemperatureRefrigerator, 36-46°F (2-8°C), in the original carton
FreezerDo not freeze
ShakingDo not shake
Out of the fridgeUp to 77°F (25°C) in the carton; use within 30 days or discard
Before the injectionSit at room temperature for at least 30 minutes; do not warm any other way (2.3)

Who stores Evenity?

Section 2.1 says Evenity should be given by a healthcare provider. Each monthly 210 mg dose is two 105 mg prefilled syringes injected one after the other (sections 2.1 and 16.1), for 12 monthly doses. The Medication Guide covers patients who pick it up from a pharmacy: keep it in the refrigerator in the carton, and once it is out, keep it at up to 77°F (25°C) and use it within 30 days. It adds that warm temperatures will affect how Evenity works.

See the Evenity dosing schedule, Evenity side effects, missed an Evenity dose and Evenity vs Forteo.

How do you travel with it?

If you carry Evenity from the pharmacy to the clinic, the label limit is 77°F (25°C) and 30 days once it is out of the fridge. Keep it in the carton, unshaken, and away from direct contact with an ice pack.

  • TSA allows medically necessary liquids over 3.4 oz in carry-on bags; declare them at the checkpoint for inspection.
  • Unused syringes and pen needles are allowed when they travel with the injectable medicine.
  • Ice packs and gel packs that keep medicine cool may go through frozen, partly frozen or melted.
  • Keep medicine in your carry-on, not checked luggage, where you cannot control the temperature. Do not let it touch an ice pack directly, since most labels say do not freeze.

More in the travel guide.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.
ProliaFridge in the carton; once out, up to 77°F and used within 30 days. ForteoFridge at all times except to inject; discard 28 days after first use. TymlosFridge before first use; then 30 days at 68-77°F.

Frequently asked questions

Does Evenity need to be refrigerated?+
Yes, until it is used. Once out of the fridge it can stay at up to 77°F (25°C) in the carton for up to 30 days.
How long can Evenity be out of the fridge?+
Up to 30 days, at no more than 77°F (25°C). After that the label says discard it.
Can Evenity be shaken?+
No. Section 16.2 says do not shake.

Sources

  1. Evenity (romosozumab-aqqg) injection US prescribing information, DailyMed
  2. TSA: Liquid medications
  3. TSA: Unused syringes
  4. TSA: Gel ice packs

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