How to Store Cetrotide 0.25 mg: Fridge, Use Once Mixed
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How to store Cetrotide (cetrorelix) 0.25 mg

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Keep Cetrotide 0.25 mg in the fridge at 36-46°F (2-8°C), with the packaged tray in its outer carton to protect it from light. The patient leaflet adds: a cool, dry place protected from excess moisture and heat. Once the powder is mixed with the water in the prefilled syringe, use it immediately. The current label gives no room-temperature allowance. Source: Cetrotide label, Storage and Patient Leaflet.

What does the Cetrotide label say?

Storage: “Store Cetrotide® 0.25 mg refrigerated, 2ºC - 8ºC (36ºF - 46ºF). Store the packaged tray in the outer carton in order to protect from light.”

Cetrotide 0.25 mg US label (revised July 2025): How Supplied, Storage and Patient Leaflet.
QuestionLabel answer
TemperatureRefrigerated, 36-46°F (2-8°C)
Light and moisturePackaged tray in the outer carton; cool, dry place protected from excess moisture and heat
Out of the fridgeNot stated
FreezerNot stated
After mixingUse the solution immediately after preparation
ExpirationDo not use the powder or the prefilled syringe after the date on the labels and carton

Each tray holds one vial of powder, one prefilled syringe with 1 mL of Sterile Water for Injection, and two needles. The syringe and needles are used once.

What does the leaflet say about mixing?

Dissolve the powder only with the water in the prefilled syringe, swirl gently and do not shake, since shaking makes bubbles. Do not use the solution if it has particles or is not clear. Draw up the full contents of the vial and inject right away.

See Cetrotide side effects, the Cetrotide dosing schedule and Cetrotide vs ganirelix.

How do you travel with it?

The current Cetrotide label gives no room-temperature allowance. Carry trays in their carton in an insulated bag with a cold pack, without letting them touch the pack.

  • TSA allows medically necessary liquids over 3.4 oz in carry-on bags; declare them at the checkpoint for inspection.
  • Unused syringes and pen needles are allowed when they travel with the injectable medicine.
  • Ice packs and gel packs that keep medicine cool may go through frozen, partly frozen or melted.
  • Keep medicine in your carry-on, not checked luggage, where you cannot control the temperature. Do not let it touch an ice pack directly, since most labels say do not freeze.

More in the travel guide.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.
GanirelixRoom temperature, away from light; each prefilled syringe used once. MenopurPowder at 37-77°F, fridge or room temperature; use right after mixing. Gonal-fFridge or up to 3 months at 68-77°F; 28 days after first injection. Left out of the fridgeExact room-temperature hours and days from each label, and the temperature ceiling.

Frequently asked questions

Does Cetrotide need to be refrigerated?+
Yes. The current US label says store Cetrotide 0.25 mg refrigerated at 36-46°F (2-8°C), with the tray in the outer carton to protect it from light.
Can Cetrotide be kept at room temperature?+
The current US label (revised July 2025) gives no room-temperature allowance. Ask your pharmacist about a tray that was left out.
How long is mixed Cetrotide good for?+
The leaflet says the solution should be used immediately after preparation.

Sources

  1. Cetrotide (cetrorelix acetate for injection) 0.25 mg US label, DailyMed
  2. TSA: Liquid medications
  3. TSA: Unused syringes
  4. TSA: Gel ice packs

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