Short answer: The Crinone Patient Information says: if you miss a dose of Crinone, use it as soon as you remember. It also says not to use more Crinone than the dose prescribed by your doctor. The leaflet does not give a cut-off for when the next dose is near; that is a question for your fertility team.
| Situation | What the label says |
|---|---|
| Schedule (ART) | 8% gel (90 mg) vaginally once daily, or twice daily with ovarian failure (Dosage and Administration) |
| Missed a dose | Use it as soon as you remember (Patient Information) |
| Doubling up | Do not use more than the prescribed dose (Patient Information) |
| Next dose near | Not addressed in the label |
The prescribing information has no missed-dose instruction. The Patient Information, which is part of the same FDA label, says: if you miss a dose of Crinone, use it as soon as you remember. Do not use more Crinone than the dose prescribed by your doctor.
The leaflet does not say what to do if the missed dose is close to the next one, or how a missed dose affects an IVF cycle. In an Assisted Reproductive Technology program, timing is set by the clinic, so those questions go to your fertility team.
The Patient Information says a discharge that may look like vaginal discharge can come from gel that remains in the vagina, even several days after use, and that this is normal.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.