Short answer: The Femring label starts at the 0.05 mg/day ring for both hot flashes and vaginal atrophy, with dose changes guided by response and attempts to taper or stop every 3 to 6 months. The ring stays in the vagina for 90 days, then is removed and, if treatment continues, replaced with a new ring. A ring that comes out early is rinsed with warm water and put back.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Femring is approved for: Femring is a soft vaginal ring that releases estradiol at a rate equivalent to 0.05 mg or 0.10 mg per day for 3 months. It is approved to treat moderate to severe hot flashes (vasomotor symptoms) and moderate to severe vulvar and vaginal atrophy due to menopause (sections 1.1, 1.2, 3).
Source
FEMRING (estradiol acetate vaginal ring) prescribing information and Patient Information. Millicent US. DailyMed, version published December 19, 2025. DailyMed setid 7aaa97f9-a9d1-c815-e053-2991aa0afb9e
Femring is inserted into the vagina by the woman herself and stays in place for 90 days (Patient Information).
After 90 days it is removed by gently pulling downwards and forwards; if treatment continues, a new ring is inserted (Patient Information, Instructions for Use).
It may be left in during sex. If it comes out, it is cleaned with warm water and put back (Instructions for Use).
Each ring is packaged singly; strengths are 0.05 mg/day and 0.10 mg/day (sections 3, 16.1).
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Item | What the label says |
|---|---|
| Start (hot flashes or vaginal atrophy) | 0.05 mg/day |
| Adjustment | Guided by the clinical response |
| Review | Attempt to taper or discontinue at 3 to 6 month intervals |
| Wear time | 90 days, then remove and replace if treatment continues |
| 0.05 mg/day ring | 12.4 mg estradiol acetate; NDC 72495-201-05 |
| 0.10 mg/day ring | 24.8 mg estradiol acetate; NDC 72495-202-10 |
For a postmenopausal woman with a uterus, a progestin should generally also be considered to reduce endometrial cancer risk. A woman without a uterus does not need one, though some with a history of endometriosis may.
Estrogen is used at the lowest effective dose for the shortest duration consistent with treatment goals and risks, with periodic re-evaluation.
After 90 days, Femring may no longer release enough medicine to control menopausal symptoms, so it is removed and replaced if treatment is still needed.
Femring can come out if it is not in far enough, with hard pushing during a bowel movement, or with weak vaginal muscles. If it comes out often, the healthcare provider is told.
There is no daily dose to miss. If Femring comes out before 90 days, it is cleaned with warm water and put back in. If it is lost, a new Femring is put in place for 90 days (Instructions for Use).
In Dose Track you set up Femring as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.