How to Store Vivelle-Dot and Minivelle Patches
[Storage · Vivelle-Dot and Minivelle]

How to store Vivelle-Dot and Minivelle (estradiol patches)

Quoted from the US label · Unopened vs in use · Travel · Sources · Reviewed

Short answer: Store Vivelle-Dot and Minivelle at room temperature, 68-77°F (20-25°C), with excursions allowed to 59-86°F (15-30°C). Do not store patches outside their pouches. Fold a used patch sticky side together, put it in a sturdy child-proof container, and put that in the trash; do not flush it. Sources: both labels, section 16 and patient leaflets.

What do the labels say?

Both labels have the same section 16.2 wording in substance. Minivelle: “Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F) [see USP Controlled Room Temperature] Do not store unpouched.”

Vivelle-Dot and Minivelle US prescribing information, section 16, and patient leaflets.
QuestionLabel answer
Temperature68-77°F (20-25°C)
Excursions59-86°F (15-30°C)
PackagingEach patch in its own pouch; patient calendar pack of 8 systems
Out of the pouchDo not store unpouched
RefrigeratorNot stated
Used patchesFold sticky side together, child-proof container, trash; do not flush

How do you throw away a used patch?

Section 16: “To discard, fold the sticky side of the transdermal system together, place it in a sturdy child-proof container, and place this container in the trash. Used transdermal systems should not be flushed in the toilet.” The patient leaflets say the same. Remove the old patch before you apply a new one.

See Vivelle-Dot side effects, Minivelle side effects, the Vivelle-Dot and Minivelle dosing schedules, Climara vs Vivelle-Dot and the estradiol page.

How do you travel with them?

Patches are a room-temperature product, so they need no ice pack. Keep them sealed in their pouches in your carry-on, within 59-86°F (15-30°C), and out of a hot car. Bring a sturdy container if you will need to throw away used patches on the trip.

Quoted from the current US label on DailyMed, not personalized advice. Labels change; the leaflet in your own carton, your pharmacist and your prescriber are the final word on how to store it.

Frequently asked questions

Do Vivelle-Dot or Minivelle patches need to be refrigerated?+
No. Both labels say store at 68-77°F (20-25°C), with excursions allowed to 59-86°F (15-30°C).
Can I keep patches out of their pouches?+
No. Both labels say do not store the patches outside their pouches.
Can I flush a used estradiol patch?+
No. Fold the sticky side together, put it in a sturdy child-proof container and put that in the trash. The labels say used patches should not be flushed.