Short answer: Section 2.7 of the Xigduo XR label says a missed dose is taken as soon as possible, without doubling up the next dose. The Medication Guide adds: if it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Xigduo XR is taken once daily in the morning with food.
| Situation | What the label says |
|---|---|
| Schedule | Once daily in the morning with food; swallowed whole (2.2) |
| Missed a dose | Take it as soon as possible (2.7) |
| Almost time for the next dose | Skip the missed dose (Medication Guide) |
| Doubling up | Do not take 2 doses at the same time (2.7, Medication Guide) |
Section 2.7 says: "If a dose is missed, instruct patients to take the dose as soon as possible. Advise patients not to double up the next dose."
The Medication Guide says: "If you miss a dose of XIGDUO XR, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take 2 doses of XIGDUO XR at the same time."
The missed-dose wording does not say. Section 2.2 says Xigduo XR is taken once daily in the morning with food and swallowed whole, never crushed, cut or chewed.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.