Short answer: The Prometrium label has no missed-dose instructions in the prescribing information or Patient Information. It describes a single daily dose at bedtime, because of possible dizziness and drowsiness: 200 mg for 12 days in a row per 28-day cycle alongside estrogen, or 400 mg for 10 days for missed periods. Ask your prescriber or pharmacist what to do.
| Situation | What the label says |
|---|---|
| With estrogen after menopause | 200 mg at bedtime for 12 days in a row per 28-day cycle (Dosage and Administration) |
| Secondary amenorrhea | 400 mg at bedtime for 10 days (Dosage and Administration) |
| Missed-dose rule | None in the label |
| Why bedtime | Possible dizziness and drowsiness (Dosage and Administration) |
No. We checked the Prometrium prescribing information and Patient Information on DailyMed. Neither says what to do after a missed capsule. The label gives a single daily dose at bedtime.
The Dosage and Administration section says the dose is given at bedtime because some women feel dizzy or drowsy after taking it. The label does not say whether a missed bedtime dose can be taken the next morning, or whether the 12-day or 10-day course is lengthened.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.