Short answer: The Premarin Patient Information says to take a missed dose as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your normal schedule. Do not take 2 doses at the same time. Premarin is one tablet taken at the same time each day.
| Situation | What the label says |
|---|---|
| Schedule | One tablet at the same time each day, or in cycles such as 25 days on and 5 off (2.1, Patient Information) |
| Missed a dose | Take it as soon as possible (Patient Information) |
| Almost time for the next dose | Skip it; back to your normal schedule (Patient Information) |
| Doubling up | Do not take 2 doses at the same time (Patient Information) |
The prescribing information has no missed-dose instruction. The Patient Information, which is part of the same FDA label, says: take one Premarin tablet at the same time each day. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your normal schedule. Do not take 2 doses at the same time.
Example: you take Premarin at breakfast and remember at lunch. Under the leaflet you would take it then. If you only remember the next morning, you would take that morning's tablet only.
Section 2.1 allows Premarin to be taken daily or in cycles, such as 25 days on and 5 days off. The leaflet's missed-dose wording does not separate the two. It does not say what to do with a tablet missed on the last day of a cycle; that is a question for your prescriber.
The Patient Information says estrogens should be used at the lowest dose possible, only as long as needed, and that you and your healthcare provider should talk regularly (for example, every 3 to 6 months) about the dose and whether you still need treatment.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.