Short answer: Section 2.7 of the Invokamet label says a missed dose is taken as soon as possible, without doubling up the next dose. The Medication Guide adds: if it is almost time for your next dose, skip the missed dose. It says not to take 2 Invokamet tablets, or more than 2 Invokamet XR tablets, at the same time.
| Situation | What the label says |
|---|---|
| Schedule | Invokamet: 1 tablet twice daily with meals. Invokamet XR: 2 tablets once daily with the morning meal (2.2) |
| Missed a dose | Take it as soon as possible (2.7) |
| Almost time for the next dose | Skip the missed dose (Medication Guide) |
| Most at one time | Invokamet: not 2 tablets. Invokamet XR: not more than 2 tablets (Medication Guide) |
Section 2.7 says: "If a dose is missed, instruct patients to take the dose as soon as possible. Advise patients not to double up the next dose."
The Medication Guide says: "If you miss a dose of INVOKAMET, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take 2 tablets of INVOKAMET at the same time."
The Medication Guide gives the same steps for Invokamet XR, with one difference in the last line: "Do not take more than 2 tablets of INVOKAMET XR at the same time." That is because the usual Invokamet XR dose is already two tablets once a day with the morning meal (section 2.2).
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.