Definition: Anemia is a condition in which the blood has fewer healthy red blood cells, or less hemoglobin, than normal, so the body gets less oxygen. NHLBI says it can cause tiredness, weakness, shortness of breath, dizziness and headaches. The most common type is iron-deficiency anemia, and it can also come from low vitamin B12, kidney disease, bleeding or some medicines.
| Test | Men | Women |
|---|---|---|
| Hemoglobin | 14 to 17 g/dL | 12 to 15 g/dL |
| Hematocrit | 41% to 50% | 36% to 44% |
These come from a complete blood count (CBC), the same test used to watch hematocrit on testosterone, where the concern is the opposite, too many red cells (polycythemia).
Epogen, an erythropoiesis-stimulating agent, is approved to treat anemia from chronic kidney disease, from zidovudine in HIV, and from some chemotherapy. Its boxed warning says that in kidney disease, aiming for a hemoglobin above 11 g/dL raised the risk of death, serious heart events and stroke, so the lowest dose that avoids transfusions is used. NIDDK lists anemia among CKD complications.
Hemoglobin and hematocrit move slowly. Keeping each CBC with its date, and notes such as heavy periods, blood donation or new tiredness, helps show whether a change is a trend or a one-off.
Read more on Dose Track: Testosterone and anemia · Epogen side effects · Epoetin alfa guide · Iron guide