Short answer: The Gattex label dose is 0.05 mg/kg of body weight injected under the skin once a day, for adults and children 1 year and older. People with an eGFR under 60 mL/min/1.73 m2 get 0.025 mg/kg once a day. Each vial is mixed with sterile water and used within 3 hours. A missed dose is taken as soon as possible that same day, never 2 doses in one day.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Gattex is approved for: Gattex is a glucagon-like peptide-2 (GLP-2) analog approved for adults and children 1 year of age and older with short bowel syndrome (SBS) who depend on parenteral support, meaning extra nutrition or fluids given by vein (section 1).
Source
GATTEX (teduglutide) for injection, for subcutaneous use, prescribing information, Medication Guide and Instructions for Use. Takeda. DailyMed, version published September 18, 2025. DailyMed setid 66b69c1e-b25c-44d3-b5ff-1c1de9a516fa
Gattex is injected under the skin only, not into a vein or muscle. The label recommends rotating sites between the thighs, upper arms and abdomen (section 2.2).
Each 5 mg vial is mixed with the 0.5 mL of sterile water in the supplied prefilled syringe, rolled gently and not shaken. At most 0.38 mL (3.8 mg) can be drawn out for a dose. The mixed solution is used within 3 hours and any leftover is thrown away (section 2.6).
The label says Gattex is for adult self-injection or caregiver injection; self-injection by children has not been tested, and the 5 mg kit is not recommended for children under 10 kg (section 2.1). The Medication Guide says it is given 1 time each day at the same time.
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Item | What the label says |
|---|---|
| Recommended dosage | 0.05 mg/kg once daily administered by subcutaneous injection |
| Who | Adults and pediatric patients 1 year of age and older |
| Renal impairment (eGFR less than 60 mL/min/1.73 m2, including end-stage renal disease) | 0.025 mg/kg once daily |
| Strength | 5 mg teduglutide in a single-dose vial, with 0.5 mL Sterile Water for Injection in a prefilled syringe |
| Injection sites | Thighs, upper arms, and the abdomen, alternating sites |
Within 6 months before starting, adults have a colonoscopy and upper endoscopy with polyp removal, and children have a stool blood test. Everyone has baseline blood tests for bilirubin, alkaline phosphatase, lipase and amylase.
Adults have a follow-up colonoscopy and upper endoscopy (or other imaging) after 1 year, then at least every 5 years. Children have a stool blood test every year and a colonoscopy after 1 year and every 5 years after that. Blood tests are repeated every 6 months.
Stopping Gattex may cause fluid and electrolyte imbalance, so fluid and electrolyte status is monitored after it is stopped.
Before dispensing, Gattex vials are kept refrigerated at 2 C to 8 C (36 F to 46 F). After the pharmacist dispenses the kit, it is stored at room temperature up to 25 C (77 F), not frozen, with a 90-day "use by" date.
The label says: "If a dose is missed, that dose should be taken as soon as possible on that day. Do not take 2 doses on the same day." The Medication Guide adds: "Take your next dose the next day at the same time you take it every day."
More on this: missed a dose of Gattex.
In Dose Track you set up Gattex as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.